SCHEMBL20149566

SCHEMBL20149566

CCCC(C)Oc1c(F)cc(N)cc1F

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.37
DHODH Q02127 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20226560 0.81 MCHR1 (0.35) MCHR1
SCHEMBL1496790 0.77 ALDH1A1 (0.31)
SCHEMBL20226628 0.74 MCHR1 (0.36) MCHR1
SCHEMBL19257770 0.72 MCHR1 (0.33) MCHR1
SCHEMBL20226508 0.72 MCHR1 (0.41) MCHR1DHODH
SCHEMBL16744728 0.72 ALOX5AP (0.32) MCHR1
SCHEMBL22150421 0.72 LPL (0.38)
SCHEMBL22150437 0.72 LPL (0.38)
SCHEMBL20226625 0.71 MCHR1 (0.38) MCHR1DHODH
SCHEMBL14308973 0.70 PTGS2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018089373-A9 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2018-07-12 WO disclosed
WO-2018089373-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2018-05-17 WO disclosed