Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 4/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.32 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.32 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16745349 | 0.97 | ALDH1A1 (0.41) | ALDH1A1S100A4TDP1POLBCYP3A4 | |
| SCHEMBL16745345 | 0.95 | ALDH1A1 (0.42) | ALDH1A1S100A4TDP1POLBCYP3A4 | |
| SCHEMBL16745341 | 0.95 | ALDH1A1 (0.44) | ALDH1A1S100A4TDP1POLBCYP3A4 | |
| SCHEMBL16745339 | 0.91 | ALDH1A1 (0.44) | ALDH1A1S100A4TDP1POLBCYP3A4 | |
| SCHEMBL18193063 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TDP1POLBCYP3A4HPGD | |
| SCHEMBL18193068 | 0.85 | ALDH1A1 (0.38) | ALDH1A1TDP1POLBCYP3A4HPGD | |
| SCHEMBL15551462 | 0.83 | S100A4 (0.42) | ALDH1A1S100A4POLBCYP3A4HPGD | |
| SCHEMBL29906291 | 0.83 | S100A4 (0.42) | ALDH1A1S100A4POLBCYP3A4HPGD | |
| SCHEMBL16745368 | 0.79 | PBRM1 (0.36) | S100A4MEN1CYP1A2MAPTKMT2A | |
| SCHEMBL16745364 | 0.79 | MAOA (0.49) | ALDH1A1TDP1POLBHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481662-B2 | Seriniquinones, melanoma-specific anticancer agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-01 | — | — | US | disclosed |
| US-9481662-B2 | Seriniquinones, melanoma-specific anticancer agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-01 | — | — | US | disclosed |
| US-20150148314-A1 | SERINIQUINONES, MELANOMA-SPECIFIC ANTICANCER AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-28 | — | — | US | disclosed |
| US-20150148314-A1 | SERINIQUINONES, MELANOMA-SPECIFIC ANTICANCER AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148314-A1 | SERINIQUINONES, MELANOMA-SPECIFIC ANTICANCER AGENTS | SDHA, KLK3, BRDT | ALDH1A1 447/4885S100A4 858/4885TDP1 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.