Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069945 | 1.00 | TLR4 (0.46) | TLR4CYP2C9POLBHPGDMAPT | |
| SCHEMBL3627200 | 1.00 | TLR4 (0.46) | TLR4CYP2C9POLBHPGDMAPT | |
| SCHEMBL9405948 | 1.00 | TLR4 (0.46) | TLR4CYP2C9POLBHPGDMAPT | |
| SCHEMBL4482942 | 0.94 | CYP2C9 (0.41) | TLR4CYP2C9POLBHPGDMAPT | |
| SCHEMBL7522154 | 0.94 | CYP2C9 (0.41) | TLR4CYP2C9POLBHPGDMAPT | |
| SCHEMBL10737849 | 0.89 | POLB (0.49) | TLR4CYP2C9POLBHPGDMAPT | |
| SCHEMBL10737844 | 0.89 | POLB (0.49) | TLR4CYP2C9POLBHPGDMAPT | |
| SCHEMBL9347924 | 0.87 | PKM (0.50) | TLR4CYP2C9POLBHPGDMAPT | |
| SCHEMBL17799607 | 0.87 | PKM (0.50) | TLR4CYP2C9POLBHPGDMAPT | |
| SCHEMBL6859266 | 0.87 | PKM (0.50) | TLR4CYP2C9POLBHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7931946-B2 | Liquid crystal compound containing sulfone group, liquid crystal composition comprising the same, and optical film using the same liquid crystal composition | LG CHEM, LTD. (KR) | 2011-04-26 | — | — | US | disclosed |
| US-7931946-B2 | Liquid crystal compound containing sulfone group, liquid crystal composition comprising the same, and optical film using the same liquid crystal composition | LG CHEM, LTD. (KR) | 2011-04-26 | — | — | US | disclosed |
| US-7931946-B2 | Liquid crystal compound containing sulfone group, liquid crystal composition comprising the same, and optical film using the same liquid crystal composition | LG CHEM, LTD. (KR) | 2011-04-26 | — | — | US | disclosed |
| US-20100096590-A1 | NOVEL LIQUID CRYSTAL COMPOUND CONTAINING SULFONE GROUP, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION | LG CHEM, LTD. (KR) | 2010-04-22 | — | — | US | disclosed |
| US-20100096590-A1 | NOVEL LIQUID CRYSTAL COMPOUND CONTAINING SULFONE GROUP, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION | LG CHEM, LTD. (KR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008091090-A1 | NOVEL LIQUID CRYSTAL COMPOUND CONTAINING SULFONE GROUP, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION | LG CHEM, LTD. (KR) | 2008-07-31 | — | — | WO | disclosed |
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |
| US-4853151-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKFTER HAFTUNG (DE) | 1989-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100096590-A1 | NOVEL LIQUID CRYSTAL COMPOUND CONTAINING SULFONE GROUP, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION | SFXN1, SOST, SFXN3 | TLR4 3593/4885CYP2C9 2691/4885POLB 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.