Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482942 | 1.00 | CYP2C9 (0.41) | CYP2C9POLBHPGDLMNAMAPT | |
| SCHEMBL9405948 | 0.94 | TLR4 (0.46) | CYP2C9POLBHPGDLMNAMAPT | |
| SCHEMBL5069945 | 0.94 | TLR4 (0.46) | CYP2C9POLBHPGDLMNAMAPT | |
| SCHEMBL1674729 | 0.94 | TLR4 (0.46) | CYP2C9POLBHPGDLMNAMAPT | |
| SCHEMBL3627200 | 0.94 | TLR4 (0.46) | CYP2C9POLBHPGDLMNAMAPT | |
| SCHEMBL10555723 | 0.89 | CYP2C9 (0.37) | CYP2C9POLBHPGDLMNAMAPT | |
| SCHEMBL10555731 | 0.89 | CYP2C9 (0.37) | CYP2C9POLBHPGDLMNAMAPT | |
| SCHEMBL10555735 | 0.89 | CYP2C9 (0.37) | CYP2C9POLBHPGDLMNAMAPT | |
| SCHEMBL1508098 | 0.88 | HTT (0.53) | CYP2C9POLBHPGDLMNAMAPT | |
| SCHEMBL1284003 | 0.88 | HTT (0.53) | CYP2C9POLBHPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071458-B | Triamide compounds and compositions comprising the same | 美利肯公司 | 2021-12-10 | — | — | CN | disclosed |
| EP-3426639-B1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & CO (US) | 2021-05-05 | — | — | EP | disclosed |
| US-10844006-B2 | Trisamide compounds and compositions comprising the same | MILLIKEN & COMPANY (US) | 2020-11-24 | — | — | US | disclosed |
| US-20170260129-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & CO (US) | 2017-09-14 | — | — | US | disclosed |
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| US-8389073-B2 | Four-ring liquid crystal compound having tetrahydropyran and 2,2′,3,3′-tetrafluorobiphenyl, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20110297881-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING TETRAHYDROPYRAN AND 2,2',3,3'-TETRAFLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO PETROCHEMICAL CORPORATION (JP) | 2011-12-08 | — | — | US | disclosed |
| WO-2010106550-A2 | A PROCESS FOR THE PREPARATION OF N-[[TRANS-4-(1-METHYLETHYL)CYCLOHEXYL]CARBONYL]-D-PHENYLALANINE | NEULAND LABORATORIES LTD. (IN) | 2010-09-23 | — | — | WO | disclosed |
| US-7488832-B2 | e.g. N-[amino(imino)methyl]-2-[2-(4-phenoxyphenyl)-5-phenyl-1H-pyrrol-1-yl]acetamide; beta -amyloid deposits and neurofibrillary tangles; cognition activator, neurodegenerative diseases; Alzheimer's disease, Down's syndrome | WYETH (US) | 2009-02-10 | — | — | US | disclosed |
| US-20080287424-A1 | AZOLYLACYLGUANIDINES AS beta-SECRETASE INHIBITORS | WYETH (US) | 2008-11-20 | — | — | US | disclosed |
| EP-0300009-A1 | LIQUID CRYSTALLINE MIXTURE. | MERCK PATENT GMBH (DE) | 1989-01-25 | — | — | EP | disclosed |
| EP-0293910-A2 | Liquid crystal composition and liquid crystal device containing same | CANON KABUSHIKI KAISHA (JP) | 1988-12-07 | — | — | EP | disclosed |
| WO-1988005803-A1 | LIQUID CRYSTALLINE MIXTURE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-08-11 | — | — | WO | disclosed |
| US-4713197-A | Nitrogen-containing heterocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-12-15 | — | — | US | disclosed |
| US-4683078-A | LIQUID CRYSTAL DIELECTRICS | CHISSO CORPORATION (JP) | 1987-07-28 | — | — | US | disclosed |
| US-4673529-A | LIQUID CRYSTALS JLMOKOUM INTEGRATED CIRCUITS | CHISSO CORPORATION (JP) | 1987-06-16 | — | — | US | disclosed |
| US-4487954-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4473487-A | 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-25 | — | — | US | disclosed |
| US-4472592-A | CYCLOHEXYL PHENYL ESTERS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4290905-A | FOR LIQUID CRYSTAL DISPLAYS | KABUSHIKI KAISHA SUWA SEIKOSHA (JP) | 1981-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844006-B2 | Trisamide compounds and compositions comprising the same | TELO2, TERT, H1-2 | CYP2C9 4183/4885POLB 1401/4885HPGD 3763/4885 |
| US-20080287424-A1 | AZOLYLACYLGUANIDINES AS beta-SECRETASE INHIBITORS | BACE1, BACE2, APP | CYP2C9 1152/4885POLB 3725/4885HPGD 2234/4885 |
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | DGAT1, DGAT2, SOAT1 | CYP2C9 2703/4885POLB 4112/4885HPGD 881/4885 |
| US-20170260129-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | TELO2, TERT, H1-2 | CYP2C9 4183/4885POLB 1401/4885HPGD 3763/4885 |
| US-20110297881-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING TETRAHYDROPYRAN AND 2,2',3,3'-TETRAFLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CCT4, TEC, TCF4 | CYP2C9 343/4885POLB 4069/4885HPGD 4186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.