Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748640 | 0.90 | SMPD1 (0.38) | GAASMPD1TP53TSHRSGPL1 | |
| SCHEMBL9915473 | 0.87 | GAA (0.42) | GAASMPD1TP53TSHRHCAR2 | |
| SCHEMBL16748687 | 0.80 | HPGD (0.43) | SMPD1KMT2APTPN1 | |
| SCHEMBL9915470 | 0.79 | SMPD1 (0.37) | GAASMPD1TP53TSHRSGPL1 | |
| SCHEMBL9915507 | 0.78 | GAA (0.46) | GAASMPD1TP53TSHRHCAR2 | |
| SCHEMBL16748705 | 0.74 | TP53 (0.37) | TP53XDHS1PR3 | |
| SCHEMBL16748690 | 0.73 | MAPT (0.41) | SMPD1TP53TSHRKMT2A | |
| SCHEMBL12334449 | 0.71 | SMPD1 (0.63) | GAASMPD1TP53TSHRHCAR2 | |
| SCHEMBL9915495 | 0.70 | SMPD1 (0.41) | SMPD1S1PR3 | |
| SCHEMBL9915469 | 0.69 | SMPD1 (0.40) | GAASMPD1TP53TSHRSGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646436-B1 | MONOBACTAMS | PFIZER (US) | 2015-05-27 | — | — | EP | disclosed |