Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
| ▸ | FABP4 | P15090 | 3/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16750276 | 0.86 | ENPP2 (0.59) | ENPP2FABP4TBXA2RHDAC1HDAC6 | |
| SCHEMBL18070807 | 0.80 | ENPP2 (0.42) | ENPP2FABP4TBXA2RMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL18044820 | 0.79 | ENPP2 (0.41) | ENPP2FABP4TBXA2RMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL18044819 | 0.79 | ENPP2 (0.41) | ENPP2FABP4TBXA2RMAPTKDM4E | |
| SCHEMBL16750321 | 0.75 | ENPP2 (0.47) | ENPP2HDAC1HDAC6PTGS1PTGS2 | |
| SCHEMBL16750267 | 0.74 | ENPP2 (0.46) | ENPP2HDAC1HDAC6PTGDR2 | |
| SCHEMBL20248013 | 0.73 | ENPP2 (0.52) | ENPP2TBXA2RKDM4EHDAC1HDAC6 | |
| SCHEMBL16750334 | 0.73 | ENPP2 (0.72) | ENPP2HDAC1HDAC6PTGS1PTGS2 | |
| SCHEMBL18044821 | 0.71 | ENPP2 (0.56) | ENPP2FABP4TBXA2RHDAC1HDAC6 | |
| SCHEMBL16742433 | 0.70 | ENPP2 (0.52) | ENPP2FABP4TBXA2RCYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264575-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | DF 2024 IP ACQUISITION, LLC | 2016-09-15 | — | — | US | disclosed |
| WO-2015077502-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | PHARMAKEA, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264575-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | ENPP2, SERPINB1, UACA | ENPP2 1/4885FABP4 2454/4885TBXA2R 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.