SCHEMBL16751645

SCHEMBL16751645

c1cnc2c(c1)[nH]c1oc3cncnc3c12

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 6/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GRM4 Q14833 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36
PARP1 P09874 3/20 0.35
METAP2 P50579 2/20 0.34
METAP1 P53582 2/20 0.34
MAPK14 Q16539 1/20 0.32
PKM P14618 1/20 0.32
KDM4E B2RXH2 1/20 0.31
KIF11 P52732 1/20 0.31
NUDT1 P36639 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16751755 0.89 MAPK14 (0.34) KCNMA1GABRA1GABRG2GABRB3GABRA5
SCHEMBL16751648 0.85 MAPK14 (0.33) MAPK14
SCHEMBL16751670 0.81 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL16751659 0.79 GABRA1 (0.40) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL16751698 0.77 KCNMA1 (0.41) KCNMA1GABRA1GABRG2GABRB3GABRA5
SCHEMBL16751652 0.77 GABRA1 (0.39) KCNMA1GABRA1GABRG2GABRB3GABRA5
SCHEMBL16751608 0.75 PARP1 (0.47) KCNMA1GABRA1GABRG2GABRB3GABRA5
SCHEMBL16751618 0.73 MAPK14 (0.36) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL12590228 0.73 GABRA1 (0.47) KCNMA1GABRA1GABRG2GABRB3GABRA5
SCHEMBL22483134 0.73 MAPK14 (0.39) GRM4METAP2METAP1MAPK14KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015076600-A1 NOVEL LIGHT EMISSION COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 동진쎄미켐 2015-05-28 WO disclosed