SCHEMBL16751652

SCHEMBL16751652

c1cnc2c(c1)[nH]c1oc3ccncc3c12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.39
GABRG2 P18507 4/20 0.39
GABRB3 P28472 4/20 0.39
GABRA5 P31644 4/20 0.39
GABRA3 P34903 4/20 0.39
GABRA2 P47869 4/20 0.39
ACHE P22303 1/20 0.38
PARP1 P09874 4/20 0.38
KCNMA1 Q12791 2/20 0.36
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36
CDK4 P11802 1/20 0.35
CCND1 P24385 1/20 0.35
KDM4E B2RXH2 2/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
IKBKB O14920 1/20 0.35
AURKA O14965 1/20 0.35
CHUK O15111 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16751608 0.84 PARP1 (0.47) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL16751753 0.81 ACHE (0.53) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL16751752 0.80 GABRA1 (0.43) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL16751644 0.77 CHUK (0.43) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL16751645 0.77 KCNMA1 (0.36) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL16751762 0.76 PARP1 (0.45) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL16751757 0.75 GABRA1 (0.48) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL11885009 0.73 MAPK14 (0.42) KDM4EALDH1A1HPGDMAOATDO2
SCHEMBL16751759 0.72 ACHE (0.53) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL12590218 0.72 ACHE (0.61) GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015076600-A1 NOVEL LIGHT EMISSION COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 동진쎄미켐 2015-05-28 WO disclosed