SCHEMBL16751698

SCHEMBL16751698

c1cnc2c(c1)[nH]c1oc3nccnc3c12

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 8/20 0.41
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40
PARP1 P09874 3/20 0.39
GABRA1 P14867 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA2 P47869 1/20 0.37
PKM P14618 1/20 0.35
NUDT1 P36639 1/20 0.35
METAP2 P50579 1/20 0.35
METAP1 P53582 1/20 0.35
KDM4E B2RXH2 1/20 0.35
KIF11 P52732 1/20 0.35
PSMD14 O00487 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16751762 0.85 PARP1 (0.45) KCNMA1ADORA3ADORA2APARP1GABRA1
SCHEMBL16751748 0.82 GABRA1 (0.42) PARP1GABRA1GABRG2GABRB3GABRA5
SCHEMBL16751645 0.77 KCNMA1 (0.36) KCNMA1ADORA3ADORA2APARP1GABRA1
SCHEMBL16751608 0.74 PARP1 (0.47) KCNMA1ADORA3ADORA2APARP1GABRA1
SCHEMBL16751750 0.73 GABRA1 (0.43) PARP1GABRA1GABRG2GABRB3GABRA5
SCHEMBL16751702 0.73 GABRA1 (0.42) ADORA3ADORA2APARP1GABRA1GABRG2
SCHEMBL16751652 0.71 GABRA1 (0.39) KCNMA1ADORA3ADORA2APARP1GABRA1
SCHEMBL16751618 0.70 MAPK14 (0.36) PARP1GABRA1GABRG2GABRB3GABRA5
SCHEMBL12396542 0.69 PARP1 (0.55) KCNMA1ADORA3ADORA2APARP1GABRA1
SCHEMBL30322789 0.69 PARP1 (0.55) KCNMA1ADORA3ADORA2APARP1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015076600-A1 NOVEL LIGHT EMISSION COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 동진쎄미켐 2015-05-28 WO disclosed