SCHEMBL16751979

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13702081	0.79	ABL1 (0.49)	ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
	SCHEMBL14137207	0.78	JAK2 (0.54)	ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A
	SCHEMBL16751973	0.76	FFAR2 (0.47)	IDO1ALDH1A1KDM4ESMN1; SMN2NPC1
	SCHEMBL29027756	0.75	AAK1 (0.41)	IDO1ALDH1A1NPSR1FPR2EPHX1
	SCHEMBL29027753	0.75	AAK1 (0.41)	IDO1ALDH1A1NPSR1FPR2EPHX1
	SCHEMBL17673351	0.74	ABL1 (0.48)	ALDH1A1SMN1; SMN2NPC1RAB9AFPR2
	SCHEMBL17673338	0.73	ABL1 (0.54)	ALDH1A1SMN1; SMN2NPC1RAB9AABL1
	SCHEMBL16751938	0.73	FFAR2 (0.45)	ALDH1A1NPSR1SMN1; SMN2FPR2FPR3
	SCHEMBL24103525	0.72	RAB9A (0.54)	ALDH1A1SMN1; SMN2NPC1RAB9ATSHR
	SCHEMBL1432592	0.71	PTK2 (0.50)	IDO1KDM4ERAB9AHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.