Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12255202 | 0.90 | ALDH1A1 (0.50) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL5542953 | 0.80 | ALDH1A1 (0.46) | GAAALDH1A1MAPK1TSHRL3MBTL1 | |
| SCHEMBL1885468 | 0.80 | ALDH1A1 (0.58) | CA2GAAALDH1A1MAPK1TSHR | |
| SCHEMBL2400474 | 0.80 | KMT2A (0.51) | GAAALDH1A1TSHRL3MBTL1CYP19A1 | |
| SCHEMBL2651928 | 0.80 | ALDH1A1 (0.55) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL11038201 | 0.78 | CYP1A2 (0.47) | MAOAGAAALDH1A1MAPTMAPK1 | |
| SCHEMBL13481189 | 0.78 | KLK7 (0.52) | GAAALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL11002749 | 0.78 | LMNA (0.58) | GAAALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL1125428 | 0.78 | ALDH1A1 (0.45) | GAAALDH1A1MAPK1TSHRL3MBTL1 | |
| SCHEMBL11776327 | 0.78 | TSHR (0.63) | ALDH1A1MAPTTSHRL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |