SCHEMBL2651928

SCHEMBL2651928

CCCSc1ccc(CC(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
HSD17B10 Q99714 4/20 0.55
HPGD P15428 3/20 0.55
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
CA2 P00918 2/20 0.48
CAMK2A Q9UQM7 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA7 P43166 1/20 0.47
CA13 Q8N1Q1 1/20 0.47
AKR1B1 P15121 1/20 0.47
TSHR P16473 3/20 0.46
LMNA P02545 2/20 0.46
GAA P10253 2/20 0.46
ABCC4 O15439 1/20 0.46
PTGS1 P23219 1/20 0.46
HTT P42858 1/20 0.46
PLA2G4B P0C869 1/20 0.44
KLKB1 P03952 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1403717 0.85 ALDH1A1 (0.53) ALDH1A1HSD17B10HPGDMAOACA2
SCHEMBL31632669 0.83 CA2 (0.50) ALDH1A1HSD17B10HPGDCA2CAMK2A
SCHEMBL12255202 0.80 ALDH1A1 (0.50) ALDH1A1HSD17B10MAOAMAOBCA2
SCHEMBL167520 0.80 MAOA (0.45) ALDH1A1HSD17B10MAOAMAOBCA2
SCHEMBL670933 0.78 PKM (0.51) ALDH1A1HSD17B10HPGDCA2CAMK2A
SCHEMBL6403659 0.77 CA2 (0.47) ALDH1A1HSD17B10HPGDMAOACA2
SCHEMBL1017821 0.77 HTT (0.51) ALDH1A1MAOAMAOBCA2CA12
SCHEMBL11690462 0.77 CA2 (0.52) ALDH1A1HSD17B10HPGDCA2CAMK2A
SCHEMBL11301284 0.77 CA2 (0.52) ALDH1A1HSD17B10HPGDCA2CAMK2A
SCHEMBL13397872 0.77 CA12 (0.61) ALDH1A1HPGDMAOAMAOBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109803956-B Novel benzamide compound, process for producing the same, and acaricide 日本欧爱特农业科技株式会社 2023-08-29 CN disclosed
EP-3484855-B1 NOVEL BENZYLAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, AND MITICIDE OAT AGRIO CO LTD (JP) 2022-02-23 EP disclosed
US-11000037-B2 Benzylamide compound, method for producing the same, and miticide OAT AGRIO CO., LTD. (JP) 2021-05-11 US disclosed
US-20190281824-A1 NOVEL BENZYLAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, AND MITICIDE OAT & IIL INDIA LABORATORIES PRIVATE LIMITED (IN) 2019-09-19 US disclosed
CN-109803956-A Novel benzamide compounds, preparation method and acaricide 杀虫剂(印度)有限公司 2019-05-24 CN disclosed
WO-2012028100-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2012-03-08 WO disclosed
EP-2168962-A2 PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS Prosidion Limited (GB) 2010-03-31 EP disclosed
EP-1594867-B1 PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS PROSIDION LTD (GB) 2008-04-09 EP disclosed
US-7214681-B2 Tri(cyclo) substituted amide compounds PROSIDION LIMITED (GB) 2007-05-08 US disclosed
EP-1594867-A2 PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS Prosidion Limited (GB) 2005-11-16 EP disclosed
US-20040181067-A1 Tri(cyclo) substituted amide compounds OSI PHARMACEUTICALS, INC. 2004-09-16 US disclosed
WO-2004072031-A2 PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS PROSIDION LIMITED (GB) 2004-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11000037-B2 Benzylamide compound, method for producing the same, and miticide CBR3, CBR1, BRD9 ALDH1A1 2726/4885HSD17B10 1977/4885HPGD 2149/4885
US-20040181067-A1 Tri(cyclo) substituted amide compounds GPR119, IAPP, SLC5A1 ALDH1A1 1595/4885HSD17B10 531/4885HPGD 1237/4885
US-20190281824-A1 NOVEL BENZYLAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, AND MITICIDE CBR3, CBR1, NOX5 ALDH1A1 2574/4885HSD17B10 1925/4885HPGD 2161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.