SCHEMBL16752128

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16752265	0.82	MAPT (0.49)	MAPTKMT2AMEN1ALDH1A1LMNA
	SCHEMBL16752195	0.76	KMT2A (0.46)	MAPTKMT2AMEN1ALDH1A1LMNA
	SCHEMBL16771373	0.74	KMT2A (0.43)	MAPTKMT2AMEN1ALDH1A1LMNA
	SCHEMBL5062898	0.72	POLB (0.55)	MAPTKMT2AMEN1ALDH1A1LMNA
	SCHEMBL16752125	0.70	KMT2A (0.44)	MAPTKMT2AMEN1ALDH1A1LMNA
	SCHEMBL30891910	0.69	MAPT (0.47)	MAPTKMT2AMEN1ALDH1A1LMNA
	SCHEMBL15091424	0.69	L3MBTL1 (0.59)	ALDH1A1POLBKDM4EUBE2NHTT
	SCHEMBL18526576	0.69	PTGER4 (0.33)	KDM4E
	SCHEMBL12253486	0.68	SLC9A1 (0.56)	MAPTKMT2AMEN1ALDH1A1LMNA
	SCHEMBL17927652	0.68	KMT2A (0.41)	MAPTKMT2AMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.