Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 15/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752440 | 0.87 | PTGS2 (0.61) | MT-CO2PTGS2MEN1USP2LMNA | |
| SCHEMBL16752441 | 0.83 | DHODH (0.67) | MT-CO2PTGS2MEN1USP2LMNA | |
| SCHEMBL10518206 | 0.81 | MT-CO2 (0.73) | MT-CO2PTGS2MEN1USP2LMNA | |
| SCHEMBL16752430 | 0.79 | PTGS2 (0.65) | MT-CO2PTGS2MEN1USP2LMNA | |
| Tolfenamic Acid SCHEMBL29389998 | 0.78 | MT-CO2 (1.00) | MT-CO2PTGS2MEN1USP2LMNA | |
| SCHEMBL12608896 | 0.78 | MT-CO2 (0.77) | MT-CO2PTGS2MEN1USP2LMNA | |
| Tolfenamic Acid SCHEMBL25190 | 0.78 | MT-CO2 (1.00) | MT-CO2PTGS2MEN1USP2LMNA | |
| Tolfenamic Acid SCHEMBL29484181 | 0.78 | MT-CO2 (1.00) | MT-CO2PTGS2MEN1USP2LMNA | |
| Tolfenamic Acid SCHEMBL8060884 | 0.78 | MT-CO2 (1.00) | MT-CO2PTGS2MEN1USP2LMNA | |
| SCHEMBL12049903 | 0.77 | MT-CO2 (0.71) | MT-CO2PTGS2MEN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2878592-B1 | SYNTHESIS OF AMIDE DERIVATIVES OF SOME NONSTEROIDAL ANTIINFLAMMATORY DRUGS AS POTENTIAL PRO-DRUGS | KUECUEKGUEZEL ILKAY (TR) | 2019-02-20 | — | — | EP | claimed |
| EP-2878592-B1 | SYNTHESIS OF AMIDE DERIVATIVES OF SOME NONSTEROIDAL ANTIINFLAMMATORY DRUGS AS POTENTIAL PRO-DRUGS | KUECUEKGUEZEL ILKAY (TR) | 2019-02-20 | — | — | EP | disclosed |
| EP-2878592-B1 | SYNTHESIS OF AMIDE DERIVATIVES OF SOME NONSTEROIDAL ANTIINFLAMMATORY DRUGS AS POTENTIAL PRO-DRUGS | KUECUEKGUEZEL ILKAY (TR) | 2019-02-20 | — | — | EP | disclosed |
| EP-2878592-A1 | Synthesis of amide derivatives of some nonsteroidal antiinflammatory drugs as potential pro-drugs | Kücükgüzel, Ilkay (TR) | 2015-06-03 | — | — | EP | disclosed |
| EP-2878592-A1 | Synthesis of amide derivatives of some nonsteroidal antiinflammatory drugs as potential pro-drugs | Kücükgüzel, Ilkay (TR) | 2015-06-03 | — | — | EP | disclosed |