SCHEMBL167530

SCHEMBL167530

Cc1nc(C(F)F)c(C(=O)Nc2ccccc2-c2ccc(Cl)c(F)c2)s1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.41
NPC1 O15118 4/20 0.41
KMT2A Q03164 6/20 0.41
CHRNA7 P36544 3/20 0.41
MEN1 O00255 3/20 0.41
MAPT P10636 1/20 0.40
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
ABL1 P00519 1/20 0.39
KDM4E B2RXH2 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
PKM P14618 1/20 0.37
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
RECQL P46063 1/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
USP2 O75604 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437135 1.00 RAB9A (0.41) RAB9ANPC1KMT2ACHRNA7MEN1
SCHEMBL12212662 0.93 MAPT (0.43) RAB9ANPC1KMT2ACHRNA7MEN1
SCHEMBL2906748 0.92 CHRNA7 (0.47) RAB9ANPC1KMT2ACHRNA7MEN1
SCHEMBL12424057 0.89 CHRM3 (0.44) RAB9AMAPTABL1KDM4ESMN1; SMN2
SCHEMBL14160059 0.89 RAB9A (0.42) RAB9ANPC1KMT2ACHRNA7MEN1
SCHEMBL10213374 0.88 KMT2A (0.52) RAB9ANPC1KMT2ACHRNA7MEN1
SCHEMBL12424050 0.87 CHRNA7 (0.42) RAB9ANPC1CHRNA7GAAABL1
SCHEMBL343339 0.87 TDP1 (0.47) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL4106877 0.87 NTRK1 (0.40) RAB9ANPC1KMT2AMEN1MAPT
SCHEMBL13210784 0.86 KMT2A (0.42) RAB9ANPC1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
EP-3381289-B1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND BAYER CROPSCIENCE LP (US) 2021-05-05 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
EP-2292098-B1 Combinations comprising a fungicidal strain and at least one additional fungicide BAYER CROPSCIENCE LP (US) 2019-11-06 EP claimed
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
EP-3381289-A1 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND Bayer Cropscience LP (US) 2018-10-03 EP claimed
US-20170318816-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BAYER CROPSCIENCE LP 2017-11-09 US claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
EP-1819223-B1 USE OF MENADIONE FOR BOOSTING THE EFFECTIVENESS OF AGROCHEMICALS BASF SE (DE) 2008-03-12 EP claimed
US-20080039320-A1 Use Of Menadione BASF AKTIENGESELLSCHAFT (DE) 2008-02-14 US claimed
WO-2007122264-A2 COMPOSITION COMPRISING A GLUCAN OR A GLUCAN DERIVATIVE AND A PESTICIDE AND METHODS FOR IMPROVING PLANT HEALTH BASF SE (DE) 2007-11-01 WO claimed
EP-1849364-A1 Composition comprising a glucan or a glucan derivative and a pesticide and methods for improving plant health BASF AKTIENGESELLSCHAFT (DE) 2007-10-31 EP claimed
WO-2007104669-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2007-09-20 WO claimed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO claimed
EP-1796468-A1 SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS WHICH CONTAIN SPIROXAMINE, A TRIAZOLE AND A CARBOXAMIDE Bayer CropScience AG (DE) 2007-06-20 EP claimed
WO-2006032356-A1 SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS WHICH CONTAIN SPIROXAMINE, A TRIAZOLE AND A CARBOXAMIDE BAYER CROPSCIENCE AG (DE) 2006-03-30 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080039320-A1 Use Of Menadione MANBA, MGAM2, MGAM RAB9A 3983/4885NPC1 4166/4885KMT2A 1399/4885
US-20170318816-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL RAB9A 3858/4885NPC1 4012/4885KMT2A 3429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.