Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437135 | 0.92 | RAB9A (0.41) | CHRNA7NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL167530 | 0.92 | RAB9A (0.41) | CHRNA7NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14160059 | 0.91 | RAB9A (0.42) | CHRNA7NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL12212662 | 0.89 | MAPT (0.43) | CHRNA7NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL343339 | 0.89 | TDP1 (0.47) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL13210784 | 0.88 | KMT2A (0.42) | CHRM3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL13210721 | 0.86 | NTRK1 (0.43) | CHRM3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4106877 | 0.85 | NTRK1 (0.40) | CHRM3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5165138 | 0.84 | CHRNA7 (0.47) | CHRNA7CHRM3NPC1RAB9AKMT2A | |
| SCHEMBL13064249 | 0.84 | TSHR (0.50) | NPC1RAB9AKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474407-B1 | DIFLUOROMETHYL THIAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-08-04 | — | — | EP | disclosed |
| US-7388097-B2 | Difluoromethyl thiazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-17 | — | — | US | disclosed |
| US-7388097-B2 | Difluoromethyl thiazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-17 | — | — | US | disclosed |
| US-7388097-B2 | Difluoromethyl thiazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-17 | — | — | US | disclosed |
| US-20050124815-A1 | Difluoromethyl thiazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124815-A1 | Difluoromethyl thiazolyl carboxanilides | MRPL21, FOXM1, FLT3 | CHRNA7 4275/4885CHRM3 493/4885NPC1 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.