SCHEMBL1675353

SCHEMBL1675353

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nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.33
P2RY10 O00398 2/20 0.32
GPR174 Q9BXC1 2/20 0.32
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL2765872 0.89 SLC7A5 (0.39) SLC7A5P2RY10GPR174SLC1A3SLC1A2
SCHEMBL1514088 0.85 SLC7A5 (0.44) SLC7A5P2RY10GPR174SLC1A3SLC1A2
SCHEMBL1514108 0.85 SLC7A5 (0.44) SLC7A5P2RY10GPR174SLC1A3SLC1A2
SCHEMBL442281 0.85 SLC7A5 (0.30) SLC7A5
Glycine SCHEMBL8005617 0.82 SLC7A5 (0.41) SLC7A5P2RY10GPR174SLC1A3SLC1A2
Threonine SCHEMBL5073183 0.81 SLC7A5 (0.38) SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL2702062 0.80 SLC7A5 (0.46) SLC7A5P2RY10GPR174SLC1A3SLC1A2
Threonine SCHEMBL6856748 0.80 SLC7A5 (0.36) SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL6038226 0.78 SLC7A5 (0.44) SLC7A5P2RY10GPR174SLC1A3SLC1A2
SCHEMBL288383 0.78 SLC7A5 (0.44) SLC7A5P2RY10GPR174SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9006170-B2 Compositions for elastogenesis and connective tissue treatment HUMAN MATRIX SCIENCES, LLC (US) 2015-04-14 US disclosed
US-8871707-B2 Elastin producing fibroblast formulations and methods of using the same HUMAN MATRIX SCIENCES, LLC (US) 2014-10-28 US disclosed
US-20110081322-A1 ELASTIN PRODUCING FIBROBLAST FORMULATIONS AND METHODS OF USING THE SAME NULASTIN, INC. 2011-04-07 US disclosed
US-7803522-B2 Elastin producing fibroblast formulations and methods of using the same HUMAN MATRIX SCIENCES, LLC (US) 2010-09-28 US disclosed
US-7560430-B2 To stimulate the endogenous production of Elastin or appear to enhance the elasticity of the skin HUMAN MATRIX SCIENCES, LLC (US) 2009-07-14 US disclosed
US-20080050346-A1 Elastin producing fibroblast formulations and methods of using the same NULASTIN, INC. 2008-02-28 US disclosed