SCHEMBL16754

SCHEMBL16754

O=S(=O)(Cl)c1c[nH]cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2226050 0.80
SCHEMBL2226048 0.77
SCHEMBL18184073 0.76
SCHEMBL18184492 0.73 LMNA (0.33)
SCHEMBL2197927 0.71 ALDH1A1 (0.35)
SCHEMBL20368331 0.69 LOXL2 (0.37)
SCHEMBL11842137 0.67 TXNRD1 (0.37)
SCHEMBL16000101 0.67 GFER (0.33)
SCHEMBL4682556 0.67
SCHEMBL8808544 0.65 MEN1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119220140-A Water-based single-component self-polishing ship antifouling paint and preparation method thereof 河北比尔尼克新材料科技股份有限公司 2024-12-31 CN claimed
CN-119081574-A Flame-retardant PET (polyethylene terephthalate) adhesive tape and preparation method thereof 常州市白鹭电器有限公司 2024-12-06 CN claimed
CN-108164536-A A kind of synthetic method for the new compound for being used to treat rheumatoid arthritis 刘双伟 2018-06-15 CN claimed
EP-4684837-A1 NOVEL MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE Temple University of the Commonwealth System of Higher Education (US) 2026-01-28 EP disclosed
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-11-06 US disclosed
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-10-16 US disclosed
US-12427124-B1 Phenylalanine-based LAT1 inhibitors and uses thereof Maxymune Therapeutics, Inc. (US) 2025-09-30 US disclosed
US-20250282790-A1 NOVEL MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE PRAEVENTIX, LLC 2025-09-11 US disclosed
EP-3541790-B1 3-(2-(4-PHENYLPIPERAZIN-1-YL)ETHYL)-2-OXA-8-AZASPIRO[4.5]DECAN-1-ONE DERIVATIVES AND RELATED COMPOUNDS AS 5-HYDROXYTRYPTAMINE RECEPTOR 7 (5-HT7) MODULATORS FOR TREATING E.G. INFLAMMATORY BOWEL DISEASE, CIRCADIAN RHYTHM DISORDER OR DEPRESSION UNIV TEMPLE (US) 2025-09-03 EP disclosed
WO-2025136811-A1 CHEMICAL COMPOUNDS AND USES THEREOF IDEAYA BIOSCIENCES, INC. (US) 2025-06-26 WO disclosed
US-12338247-B2 Modulators of the 5-hydroxytryptamine receptor 7 and their method of use TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-06-24 US disclosed
CN-1024316-C Imidazole fungicides SCHERING AGROCHEMICALS LTD (GB) 1994-04-27 CN disclosed
US-5232922-A Cardiovascular disorders HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-03 US disclosed
US-5173503-A Derivatives of N,N-dimethyl-4-phenylalkylenesulfonyl-imidazole -1-sulphonamides; phytopathogenic fungi SCHERING AGROCHEMICALS LIMITED (GB) 1992-12-22 US disclosed
US-5045557-A Imidazable fungicides and use thereof SCHERING AGROCHEMICALS LTD. (GB) 1991-09-03 US disclosed
EP-0442348-A2 Imidazole compounds, process for preparation, medicaments based on these compounds and some intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-21 EP disclosed
EP-0432892-A1 Imidazole fungicides AgrEvo UK Limited (GB) 1991-06-19 EP disclosed
EP-0284277-A1 Cyanoimidazole fungicides AgrEvo UK Limited (GB) 1988-09-28 EP disclosed
US-3932444-A PLASTICIZERS E. I. DU PONT DE NEMOURS & CO. (US) 1976-01-13 US disclosed
US-3932444-A PLASTICIZERS E. I. DU PONT DE NEMOURS & CO. (US) 1976-01-13 US disclosed