Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Xylose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xylose SCHEMBL12491343 | 1.00 | LMNA (0.39) | LMNAL3MBTL1TDP1AKR1B1ACHE | |
| Demannose SCHEMBL15559865 | 0.94 | LMNA (0.42) | LMNAL3MBTL1TDP1AKR1B1ACHE | |
| Xylose SCHEMBL8373659 | 0.91 | ALDH1A1 (0.43) | LMNAL3MBTL1TDP1 | |
| Xylose SCHEMBL13279394 | 0.85 | LMNA (0.53) | LMNAL3MBTL1TDP1AKR1B1PDE4A | |
| Xylose SCHEMBL21114394 | 0.85 | LMNA (0.53) | LMNAL3MBTL1TDP1AKR1B1PDE4A | |
| Xylose SCHEMBL290112 | 0.85 | LMNA (0.53) | LMNAL3MBTL1TDP1AKR1B1PDE4A | |
| Xylose SCHEMBL21433656 | 0.85 | LMNA (0.53) | LMNAL3MBTL1TDP1AKR1B1PDE4A | |
| Xylose SCHEMBL21114379 | 0.85 | LMNA (0.53) | LMNAL3MBTL1TDP1AKR1B1PDE4A | |
| Xylose SCHEMBL2566013 | 0.85 | LMNA (0.53) | LMNAL3MBTL1TDP1AKR1B1PDE4A | |
| Xylose SCHEMBL1331972 | 0.85 | LMNA (0.53) | LMNAL3MBTL1TDP1AKR1B1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113355307-B | Proteins | 国际N&H丹麦有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-11981942-B2 | Xylanases for solubilizing arabinoxylan-containing material | INTERNATIONAL N&H DENMARK APS (DK) | 2024-05-14 | — | — | US | disclosed |
| EP-3702450-B1 | PROTEIN | INT N&H DENMARK APS (DK) | 2024-04-10 | — | — | EP | disclosed |
| US-20230093634-A1 | XYLANASES FOR SOLUBILISING ARABINOXYLAN-CONTAINING MATERIAL | INTERNATIONAL N&H DENMARK APS (DK) | 2023-03-23 | — | — | US | disclosed |
| CN-106103707-B | Method for improving by-products of fermentation processes using xylanases | 丹尼斯科美国公司 | 2022-06-17 | — | — | CN | disclosed |
| US-20210277374-A1 | XYLANASE-CONTAINING FEED ADDITIVES FOR CEREAL-BASED ANIMAL FEED | INTERNATIONAL N&H DENMARK APS (DK) | 2021-09-09 | — | — | US | disclosed |
| CN-113355307-A | Protein | 杜邦营养生物科学有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-105992819-B | Protein | 杜邦营养生物科学有限公司 | 2021-07-13 | — | — | CN | disclosed |
| EP-3818154-A1 | XYLANASE-CONTAINING FEED ADDITIVES FOR CEREAL-BASED ANIMAL FEED | DuPont Nutrition Biosciences ApS (DK) | 2021-05-12 | — | — | EP | disclosed |
| CN-112654703-A | Xylanase-containing feed additives for cereal-based animal feed | 杜邦营养生物科学有限公司 | 2021-04-13 | — | — | CN | disclosed |
| US-20160345609-A1 | PROTEIN | INTERNATIONAL N&H DENMARK APS (DK) | 2016-12-01 | — | — | US | disclosed |
| US-20160333332-A1 | Methods for Improving By-Products from Fermentation Processes Using Xylanase | DANISCO US INC. (US) | 2016-11-17 | — | — | US | disclosed |
| CN-106103707-A | Method for improving by-products of fermentation processes using xylanases | 丹尼斯科美国公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105992819-A | Protein | 杜邦营养生物科学有限公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-105939616-A | PROCESS FOR THE PREPARATION OR A CORN-FLOUR-BASED FOODSTUFF INVOLVING APPLICATION OF XYLANASE AND CORN-BASED FOODSTUFF SUCH AS MASA-BASED FOODSTUFF OBTAINED | 杜邦营养生物科学有限公司 | 2016-09-14 | — | — | CN | disclosed |
| US-20150351433-A1 | Method | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2015-12-10 | — | — | US | disclosed |
| WO-2015114110-A1 | PROTEIN | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2015-08-06 | — | — | WO | disclosed |
| US-20150210993-A1 | Xylanases for Solubilising Arabinoxylan-Containing Material | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2015-07-30 | — | — | US | disclosed |
| CN-104740088-A | Weight reduction compound composition and preparation method thereof | HUAHONG PHARMACEUTICAL CO LTD GUANGXI ZHUANG AUTONOMOUS REGION | 2015-07-01 | — | — | CN | disclosed |
| US-20150150282-A1 | Method | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2015-06-04 | — | — | US | disclosed |