Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3373672 | 0.74 | ALDH1A1 (0.33) | ALDH1A1NOTUM | |
| Hydrochloric Acid SCHEMBL8448476 | 0.74 | ALDH1A1 (0.33) | ALDH1A1NOTUM | |
| Hydrochloric Acid SCHEMBL9065642 | 0.74 | ALDH1A1 (0.33) | ALDH1A1NOTUM | |
| SCHEMBL7638439 | 0.73 | CFTR (0.39) | ALDH1A1 | |
| SCHEMBL5892367 | 0.73 | CFTR (0.39) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16758190 | 0.72 | ALDH1A1 (0.32) | ALDH1A1NOTUM | |
| Hydrochloric Acid SCHEMBL1073648 | 0.72 | ALDH1A1 (0.32) | ALDH1A1NOTUM | |
| Hydrochloric Acid SCHEMBL1073835 | 0.72 | ALDH1A1 (0.32) | ALDH1A1NOTUM | |
| SCHEMBL5087080 | 0.71 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1485817 | 0.71 | HSD17B10 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074450-B1 | MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES | MOMENTIVE PERFORMANCE MAT INC (US) | 2020-11-11 | — | — | EP | disclosed |
| CN-105793326-B | Moisture-curable compositions with metal-arene complexes | 莫门蒂夫性能材料股份有限公司 | 2020-07-21 | — | — | CN | disclosed |
| US-10174169-B2 | Moisture curable compound with metal-arene complexes | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20170260335-A1 | MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2017-09-14 | — | — | US | disclosed |
| EP-3074450-A1 | MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES | Momentive Performance Materials Inc. (US) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015081146-A1 | MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES | MOMENTIVE PERFORMANCE MATERIALS INC (US) | 2015-06-04 | — | — | WO | disclosed |