Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1073835 | 0.77 | ALDH1A1 (0.32) | ALDH1A1NOTUM | |
| Hydrochloric Acid SCHEMBL8448476 | 0.74 | ALDH1A1 (0.33) | ALDH1A1NOTUM | |
| Hydrochloric Acid SCHEMBL16758191 | 0.74 | ALDH1A1 (0.33) | ALDH1A1NOTUM | |
| Hydrochloric Acid SCHEMBL9065642 | 0.74 | ALDH1A1 (0.33) | ALDH1A1NOTUM | |
| Fluoride Ion SCHEMBL5167398 | 0.74 | ACHE (0.37) | ALDH1A1 | |
| SCHEMBL5892367 | 0.73 | CFTR (0.39) | ALDH1A1 | |
| SCHEMBL7638439 | 0.73 | CFTR (0.39) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1073648 | 0.72 | ALDH1A1 (0.32) | ALDH1A1NOTUM | |
| Hydrochloric Acid SCHEMBL16758190 | 0.72 | ALDH1A1 (0.32) | ALDH1A1NOTUM | |
| SCHEMBL8755017 | 0.71 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123299-A1 | PREPARATION OF BIS ARYL CYCLOPENTADIENYL GROUP IVA METAL DIHALIDES | BOULDER SCIENTIFIC COMPANY (US) | 2001-08-16 | — | — | EP | claimed |
| WO-2001014389-A1 | PREPARATION OF BIS ARYL CYCLOPENTADIENYL GROUP IVA METAL DIHALIDES | BOULDER SCIENTIFIC COMPANY (US) | 2001-03-01 | — | — | WO | claimed |
| US-6124489-A | Preparation of bis aryl cyclopentadienyl Group IVA metal dihalides | BOULDER SCIENTIFIC COMPANY (US) | 2000-09-26 | — | — | US | claimed |
| WO-2010055935-A1 | ETHYLENE-α-OLEFIN COPOLYMER AND MOLDED OBJECT THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-20 | — | — | WO | disclosed |
| EP-1123299-A1 | PREPARATION OF BIS ARYL CYCLOPENTADIENYL GROUP IVA METAL DIHALIDES | BOULDER SCIENTIFIC COMPANY (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2001014389-A1 | PREPARATION OF BIS ARYL CYCLOPENTADIENYL GROUP IVA METAL DIHALIDES | BOULDER SCIENTIFIC COMPANY (US) | 2001-03-01 | — | — | WO | disclosed |
| EP-0316155-A2 | A transition-metal compound having a substituted, bridged bis-cyclopentadienyl ligand | Chisso Corporation (JP) | 1989-05-17 | — | — | EP | disclosed |