Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL16758670 | 0.96 | CES2 (0.45) | CES2CES1GPR84PPARGPPARD | |
| Hexane SCHEMBL15967387 | 0.96 | CES2 (0.45) | CES2CES1GPR84PPARGPPARD | |
| Heptane SCHEMBL3805263 | 0.96 | CES2 (0.45) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL8098761 | 0.92 | PAOX (0.48) | PAOXCES2CES1TSHRALDH1A1 | |
| Heptane SCHEMBL7356779 | 0.88 | CES2 (0.47) | CES2CES1 | |
| Pentane SCHEMBL16758664 | 0.86 | CES2 (0.39) | CES2CES1TSHRALDH1A1TDP1 | |
| Hexane SCHEMBL3032232 | 0.86 | CES2 (0.43) | CES2 | |
| Hexane SCHEMBL6279172 | 0.86 | CES2 (0.43) | CES2 | |
| Hexane SCHEMBL8467539 | 0.86 | CES2 (0.43) | CES2 | |
| Hexane SCHEMBL10364795 | 0.86 | CES2 (0.43) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074382-B1 | PELORUSIDE ANALOGS | UNIV GENT (BE) | 2017-11-15 | — | — | EP | disclosed |
| US-9771344-B2 | Peloruside analogs | UNIVERSITEIT GENT (BE) | 2017-09-26 | — | — | US | disclosed |
| US-20160304483-A1 | Peloruside Analogs | UNIVERSITEIT GENT (BE) | 2016-10-20 | — | — | US | disclosed |
| EP-3074382-A1 | PELORUSIDE ANALOGS | Universiteit Gent (BE) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015079009-A1 | PELORUSIDE ANALOGS | UNIVERSITEIT GENT (BE) | 2015-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304483-A1 | Peloruside Analogs | MAPRE1, MAPRE2, MAP1B | PAOX 1460/4885CES2 4154/4885CES1 4292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.