Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | FDPS | P14324 | 10/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL8467539 | 1.00 | CES2 (0.43) | CES2FDPSGGPS1 | |
| Hexane SCHEMBL6279172 | 1.00 | CES2 (0.43) | CES2FDPSGGPS1 | |
| Hexane SCHEMBL10364795 | 1.00 | CES2 (0.43) | CES2FDPSGGPS1 | |
| Heptane SCHEMBL7356779 | 0.98 | CES2 (0.47) | CES2FDPSGGPS1 | |
| Pentane SCHEMBL16758664 | 0.91 | CES2 (0.39) | CES2FDPS | |
| Hexane SCHEMBL16758670 | 0.90 | CES2 (0.45) | CES2 | |
| Hexane SCHEMBL15967387 | 0.90 | CES2 (0.45) | CES2 | |
| Heptane SCHEMBL3805263 | 0.90 | CES2 (0.45) | CES2 | |
| SCHEMBL8897727 | 0.89 | CES2 (0.39) | CES2FDPSGGPS1 | |
| Pentane SCHEMBL16758665 | 0.86 | PAOX (0.42) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023022523-A1 | COMPOSITION FOR PREVENTION OR TREATMENT OF NOVEL CORONAVIRUS INFECTION COMPRISING SESQUITERPENOID-BASED COMPOUND OBTAINED FROM PSIDIUMA GUAJAVA LEAF EXTRACT OR FRACTION THEREOF AS ACTIVE INGREDIENT | 서울대학교산학협력단 | 2023-02-23 | — | — | WO | disclosed |
| US-9771344-B2 | Peloruside analogs | UNIVERSITEIT GENT (BE) | 2017-09-26 | — | — | US | disclosed |
| US-20160304483-A1 | Peloruside Analogs | UNIVERSITEIT GENT (BE) | 2016-10-20 | — | — | US | disclosed |
| US-8314254-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2012-11-20 | — | — | US | disclosed |
| EP-1940863-B1 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS | NICOX SA (FR) | 2012-09-05 | — | — | EP | disclosed |
| US-20110294769-A1 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS | FERRER INTERNACIONAL S.A. (ES) | 2011-12-01 | — | — | US | disclosed |
| US-20100234229-A1 | Substituted Spirocyclic Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| US-7754654-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-07-13 | — | — | US | disclosed |
| CN-100575342-C | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG | 2009-12-30 | — | — | CN | disclosed |
| US-20090264394-A1 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS | NICOX S.A. (FR) | 2009-10-22 | — | — | US | disclosed |
| US-5284838-A | Hypotensive agents | ELF SANOFI (FR) | 1994-02-08 | — | — | US | disclosed |
| EP-0402982-B1 | Adduct-aldehyde and its use for the preparation of a vitamin-D compound | DUPHAR INT RES (NL) | 1994-01-05 | — | — | EP | disclosed |
| US-5276021-A | Anticholesterol or antilipemic agents | E. R. SQUIBB & SONS, INC. (US) | 1994-01-04 | — | — | US | disclosed |
| US-5091378-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0185814-B1 | PHENYLSERINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4695580-A | Phenylserine derivatives and processes for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| EP-0185814-A2 | Phenylserine derivatives and processes for their preparation | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0070588-B1 | METHOD OF PREPARING 1-ALPHA-HYDROXYVITAMIN D AND 1-ALPHA-HYDROXY-PREVITAMIN D COMPOUNDS, AND ADDUCT OF A PREVITAMIN D OR TACHYSTEROL COMPOUND WITH A SUITABLE DIENOPHILE | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-05-07 | — | — | EP | disclosed |
| US-4539153-A | Method of preparing 1 α-hydroxyvitamin D and 1 α-hydroxyprevitamin D compounds, and adducts of a previtamin D or tachysterol compound with a suitable dienophile | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1985-09-03 | — | — | US | disclosed |
| EP-0070588-A1 | Method of preparing 1-alpha-hydroxyvitamin D and 1-alpha-hydroxy-previtamin D compounds, and adduct of a previtamin D or tachysterol compound with a suitable dienophile | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1983-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304483-A1 | Peloruside Analogs | MAPRE1, MAPRE2, MAP1B | CES2 4154/4885FDPS 212/4885GGPS1 284/4885 |
| US-20110294769-A1 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS | NR3C1, NR3C2, NR5A1 | CES2 2425/4885FDPS 1149/4885GGPS1 815/4885 |
| US-20100234229-A1 | Substituted Spirocyclic Ketoenols | HSD17B7, CYP17A1, HSD17B11 | CES2 2667/4885FDPS 430/4885GGPS1 329/4885 |
| US-20090264394-A1 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS | NR3C1, NR3C2, NR5A1 | CES2 2425/4885FDPS 1149/4885GGPS1 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.