Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1376979 | 0.97 | HSD17B10 (0.46) | HSD17B10AKR1C3OPRM1OPRD1OPRK1 | |
| SCHEMBL4508150 | 0.82 | HSD17B10 (0.51) | HSD17B10AKR1C3USP2CYP2C9CYP3A4 | |
| SCHEMBL1675756 | 0.81 | F10 (0.46) | — | |
| SCHEMBL2760313 | 0.78 | HSD17B10 (0.57) | HSD17B10AKR1C3CYP2C9CYP3A4KMT2A | |
| SCHEMBL1675932 | 0.77 | ALDH1A1 (0.59) | USP2PSMB5KMT2AMEN1HPGD | |
| SCHEMBL3866085 | 0.77 | HSD17B10 (0.59) | HSD17B10AKR1C3CYP2C9CYP3A4KMT2A | |
| SCHEMBL30168124 | 0.77 | HSD17B10 (0.59) | HSD17B10AKR1C3CYP2C9CYP3A4KMT2A | |
| SCHEMBL8305499 | 0.77 | HSD17B10 (0.51) | HSD17B10AKR1C3CYP2C9CYP3A4PSMB5 | |
| SCHEMBL4825042 | 0.77 | GAA (0.56) | HSD17B10AKR1C3USP2CYP2C9CYP3A4 | |
| SCHEMBL7934713 | 0.76 | GAA (0.58) | HSD17B10AKR1C3CYP2C9CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4668614-B2 | — | — | 2011-04-13 | — | — | JP | claimed |