Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140423 | 0.85 | HIF1A (0.40) | KMT2AMEN1NPSR1HTTCYP1A2 | |
| SCHEMBL6139946 | 0.83 | HIF1A (0.40) | KMT2ANPSR1USP2ESR1MAPT | |
| SCHEMBL6140492 | 0.82 | MEN1 (0.40) | KMT2AMEN1NPSR1HTTCYP1A2 | |
| SCHEMBL7166322 | 0.81 | CYP2C9 (0.53) | KMT2ANPSR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7538698 | 0.75 | SIGMAR1 (0.56) | KMT2AMEN1CYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL6771290 | 0.73 | ALDH1A1 (0.65) | KMT2AMEN1HTTCYP1A2CYP2D6 | |
| SCHEMBL741751 | 0.72 | MEN1 (0.58) | KMT2AMEN1NPSR1CYP1A2CYP2D6 | |
| SCHEMBL1675928 | 0.71 | CA2 (0.43) | USP2MAPTALDH1A1LMNA | |
| SCHEMBL3864473 | 0.70 | ALDH1A1 (0.45) | KMT2AMEN1NPSR1HTTUSP2 | |
| Hydrochloric Acid SCHEMBL8550499 | 0.70 | MEN1 (0.56) | KMT2AMEN1NPSR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499591-A1 | CARBOXYLIC ACID AMIDES | MERCK PATENT GmbH (DE) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093235-A1 | CARBOXYLIC ACID AMIDES | MERCK PATENT GMBH (DE) | 2003-11-13 | — | — | WO | disclosed |