Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471128 | 0.89 | HSD11B1 (0.60) | HSD11B1MGLLLMNAHTR2A | |
| SCHEMBL6470534 | 0.85 | HSD11B1 (0.53) | HSD11B1MGLLF2F10PRSS1 | |
| SCHEMBL6470521 | 0.81 | HSD11B1 (0.53) | HSD11B1MGLLLMNAPOLBHTR2A | |
| SCHEMBL1582335 | 0.80 | HSD11B1 (0.56) | HSD11B1MGLLNPC1POLBRAB9A | |
| SCHEMBL6472809 | 0.79 | MGLL (0.57) | HSD11B1MGLLLMNAMAPT | |
| SCHEMBL6472321 | 0.78 | HSD11B1 (0.58) | HSD11B1MGLLLMNAPOLBHTR2A | |
| SCHEMBL6470683 | 0.77 | HSD11B1 (0.47) | HSD11B1MGLLLMNAPOLBHTR2A | |
| SCHEMBL6473331 | 0.76 | HSD11B1 (0.50) | HSD11B1MGLLPOLB | |
| SCHEMBL1582857 | 0.71 | HTR2A (0.70) | HSD11B1HTR2A | |
| SCHEMBL1582854 | 0.71 | HSD11B1 (0.66) | HSD11B1MGLLLMNAMAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4674686-B2 | — | — | 2011-04-20 | — | — | JP | claimed |
| JP-2006502146-A | — | — | 2006-01-19 | — | — | JP | claimed |
| EP-1546100-A1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK Corporation (KR) | 2005-06-29 | — | — | EP | claimed |
| WO-2004018423-A1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK CORPORATION (KR) | 2004-03-04 | — | — | WO | claimed |
| EP-1546100-A1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK Corporation (KR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004018423-A1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK CORPORATION (KR) | 2004-03-04 | — | — | WO | disclosed |