Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.60 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676004 | 0.89 | HSD11B1 (0.56) | HSD11B1MGLLHTR2ALMNA | |
| SCHEMBL6472809 | 0.86 | MGLL (0.57) | HSD11B1MGLLLMNAKMT2A | |
| SCHEMBL6472321 | 0.84 | HSD11B1 (0.58) | HSD11B1MGLLMC4RHTR2AALDH1A1 | |
| SCHEMBL6470683 | 0.83 | HSD11B1 (0.47) | HSD11B1MGLLHTR2AALDH1A1LMNA | |
| SCHEMBL6470521 | 0.82 | HSD11B1 (0.53) | HSD11B1MGLLMC4RHTR2AALDH1A1 | |
| SCHEMBL1582908 | 0.79 | HSD11B1 (0.60) | HSD11B1MGLLMC4RHTR2A | |
| SCHEMBL6470534 | 0.79 | HSD11B1 (0.53) | HSD11B1MGLLHTR2A | |
| SCHEMBL6473331 | 0.77 | HSD11B1 (0.50) | HSD11B1MGLLALDH1A1SMN1; SMN2 | |
| SCHEMBL6214094 | 0.76 | HSD11B1 (1.00) | HSD11B1MGLLALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1582666 | 0.74 | HSD11B1 (0.59) | HSD11B1MGLLMC4RHTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546100-A1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK Corporation (KR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004018423-A1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK CORPORATION (KR) | 2004-03-04 | — | — | WO | disclosed |