Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472321 | 0.91 | HSD11B1 (0.58) | HSD11B1LMNAALDH1A1SMN1; SMN2CCR3 | |
| SCHEMBL6472809 | 0.87 | MGLL (0.57) | HSD11B1MEN1KMT2ALMNAMGLL | |
| SCHEMBL6471128 | 0.83 | HSD11B1 (0.60) | HSD11B1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6470521 | 0.82 | HSD11B1 (0.53) | HSD11B1LMNAALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL6470699 | 0.82 | MEN1 (0.51) | MEN1KMT2AALDH1A1MGLLPOLB | |
| SCHEMBL6470534 | 0.80 | HSD11B1 (0.53) | HSD11B1HTR2AMGLL | |
| SCHEMBL6470687 | 0.79 | HSD11B1 (0.45) | HSD11B1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL1582751 | 0.78 | HSD11B1 (0.47) | HSD11B1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6473331 | 0.78 | HSD11B1 (0.50) | HSD11B1ALDH1A1SMN1; SMN2MGLLPOLB | |
| SCHEMBL1676004 | 0.77 | HSD11B1 (0.56) | HSD11B1LMNAHTR2AMGLLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546100-A1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK Corporation (KR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004018423-A1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK CORPORATION (KR) | 2004-03-04 | — | — | WO | disclosed |