SCHEMBL1676018

SCHEMBL1676018

COc1cc(OC)c2c(=O)cc(-c3cc(OC)c(O)c(OC)c3)oc2c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 4/20 0.78
KDM4E B2RXH2 4/20 0.70
MAPT P10636 3/20 0.70
POLB P06746 2/20 0.70
RECQL P46063 1/20 0.70
AKR1B1 P15121 1/20 0.70
MAOA P21397 1/20 0.70
MAPK8 P45983 1/20 0.70
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
NPC1 O15118 2/20 0.69
ABCG2 Q9UNQ0 2/20 0.69
ALDH1A1 P00352 1/20 0.69
RAB9A P51151 1/20 0.69
BRD4 O60885 1/20 0.63
PPARG P37231 1/20 0.60
LCK P06239 1/20 0.60
FLT3 P36888 2/20 0.58
MKNK2 Q9HBH9 1/20 0.58
IP6K2 Q9UHH9 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16150088 0.90 MAOA (0.85) ABCB1KDM4EMAPTPOLBRECQL
SCHEMBL20271922 0.89 BRD4 (0.71) ABCB1KDM4EMAPTPOLBRECQL
SCHEMBL5135091 0.89 MAOA (0.82) ABCB1KDM4EMAPTPOLBRECQL
SCHEMBL4165061 0.88 ABCB1 (0.81) ABCB1KDM4EMAPTPOLBRECQL
SCHEMBL29465904 0.87 ABCB1 (1.00) ABCB1KDM4EMAPTPOLBRECQL
SCHEMBL1422009 0.87 ABCB1 (1.00) ABCB1KDM4EMAPTPOLBRECQL
SCHEMBL16894639 0.87 ABCB1 (0.83) ABCB1KDM4EMAPTPOLBRECQL
SCHEMBL22686278 0.86 KDM4E (0.82) ABCB1KDM4EMAPTPOLBRECQL
SCHEMBL311530 0.85 ABCB1 (0.82) ABCB1KDM4EMAPTPOLBMAOA
SCHEMBL29978577 0.85 ABCB1 (0.82) ABCB1KDM4EMAPTPOLBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260096569-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES APEEL TECH INC (US) 2026-04-09 US claimed
EP-4496476-A1 GAS PHASE TREATMENT OF PRODUCE Apeel Technology, Inc. (US) 2025-01-29 EP claimed
CN-119156138-A Vapor treatment of agricultural products 阿比尔技术公司 2024-12-17 CN claimed
CN-117320559-A Edible coating with antimicrobial properties 阿比尔技术公司 2023-12-29 CN claimed
WO-2023183341-A1 GAS PHASE TREATMENT OF PRODUCE APEEL TECHNOLOGY, INC. (US) 2023-09-28 WO claimed
EP-4090167-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES Apeel Technology, Inc. (US) 2022-11-23 EP claimed
US-20220330565-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES APEEL TECHNOLOGY, INC. 2022-10-20 US claimed
WO-2022217089-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES APEEL TECHNOLOGY, INC. (US) 2022-10-13 WO claimed
US-20200095627-A1 MOLECULAR SENSORS AND USES THEREOF NEW YORK UNIVERSITY 2020-03-26 US claimed
US-9669003-B2 Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs JIN YONGRI (CN) 2017-06-06 US claimed
US-20150196529-A1 USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS JIN YONGRI (CN) 2015-07-16 US claimed
CN-121970752-A Application of chrysin dimethyl ether and sakurin in preventing and treating wheat scab 青岛农业大学 2026-05-05 CN disclosed
CN-121970752-A Application of chrysin dimethyl ether and sakurin in preventing and treating wheat scab 青岛农业大学 2026-05-05 CN disclosed
US-20260096569-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES APEEL TECH INC (US) 2026-04-09 US disclosed
US-12590094-B2 Compounds for the treatment of neurodegenerative and metabolic disorders UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-03-31 US disclosed
EP-0714296-B1 FLAVONOID AND BIFLAVONOID DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR ANXIOLYTIC ACTIVITY UNIV STRATHCLYDE (GB) 2001-11-07 EP disclosed
US-6004998-A FLAVONOID 6,8-DIBROMOCHRYSIN UNIVERSITY OF STRATHCLYDE (GB) 1999-12-21 US disclosed
US-5756538-A REDUCING THE SEDATIVE AND RELAXANT SIDE EFFECT UNIVERSITY OF STRATHCLYDE (GB) 1998-05-26 US disclosed
EP-0714296-A1 FLAVONOID AND BIFLAVONOID DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR ANXIOLYTIC ACTIVITY UNIVERSITY OF STRATHCLYDE (GB) 1996-06-05 EP disclosed
WO-1995005169-A1 FLAVONOID AND BIFLAVONOID DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR ANXIOLYTIC ACTIVITY THE UNIVERSITY OF STRATHCLYDE (GB) 1995-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590094-B2 Compounds for the treatment of neurodegenerative and metabolic disorders TXN2, SMN1; SMN2, SNCA ABCB1 3333/4885KDM4E 4079/4885MAPT 33/4885
US-20150196529-A1 USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS CYP2D6, GATAD2A, CYP3A43 ABCB1 218/4885KDM4E 437/4885MAPT 1508/4885
US-20260096569-A1 EDIBLE COATING WITH ANTIMICROBIAL PROPERTIES CYP51A1, ERG28, NISCH ABCB1 4347/4885KDM4E 1123/4885MAPT 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.