Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1675511 | 0.85 | KMT2A (0.57) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL16285261 | 0.83 | GLO1 (0.65) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL1676043 | 0.82 | MEN1 (0.77) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL2391130 | 0.82 | MEN1 (0.77) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL2811819 | 0.82 | MAPT (0.60) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL2811822 | 0.82 | MAPT (0.60) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL2811815 | 0.82 | MAPT (0.60) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL1676278 | 0.82 | KMT2A (0.54) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL1680043 | 0.82 | KMT2A (0.58) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL10085360 | 0.82 | ALDH1A1 (0.53) | MAPTKMT2AMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174065-B2 | Antidiabetic enolic glucoside of phenylpyruvic acid | ZADEC APS (DK) | 2019-01-08 | — | — | US | disclosed |
| US-20160083411-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | ZADEC APS (DK) | 2016-03-24 | — | — | US | disclosed |
| US-20160083411-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | ZADEC APS (DK) | 2016-03-24 | — | — | US | disclosed |
| US-9221860-B2 | Antidiabetic enolic glucoside of phenylpyruvic acid | ZADEC APS (DK) | 2015-12-29 | — | — | US | disclosed |
| US-9221860-B2 | Antidiabetic enolic glucoside of phenylpyruvic acid | ZADEC APS (DK) | 2015-12-29 | — | — | US | disclosed |
| EP-2625184-B1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | ZADEC APS (DK) | 2014-10-01 | — | — | EP | disclosed |
| US-20130310331-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | ZADEC APS (DK) | 2013-11-21 | — | — | US | disclosed |
| WO-2012045363-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | ZADEC APS (DK) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174065-B2 | Antidiabetic enolic glucoside of phenylpyruvic acid | PC, SLC5A1, SLC5A2 | MAPT 2914/4885KMT2A 4011/4885MEN1 3508/4885 |
| US-20160083411-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | PC, SLC5A1, SLC5A2 | MAPT 2914/4885KMT2A 4011/4885MEN1 3508/4885 |
| US-20130310331-A1 | ANTIDIABETIC ENOLIC GLUCOSIDE OF PHENYLPYRUVIC ACID | PC, SLC5A1, SLC5A2 | MAPT 2914/4885KMT2A 4011/4885MEN1 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.