Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414519 | 0.83 | MEN1 (0.51) | TSHRTRPA1MEN1KMT2AHTR2A | |
| SCHEMBL27991493 | 0.79 | TSHR (0.47) | TSHRTRPA1PBRM1MEN1KMT2A | |
| SCHEMBL16768482 | 0.79 | TSHR (0.38) | TSHRTRPA1PBRM1MEN1KMT2A | |
| SCHEMBL6455092 | 0.78 | NPC1 (0.38) | TSHRMEN1KMT2AHTR2ATAAR1 | |
| SCHEMBL21367527 | 0.74 | PBRM1 (0.36) | TSHRTRPA1PBRM1MEN1KMT2A | |
| SCHEMBL5163408 | 0.70 | ACP3 (0.43) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5557026 | 0.70 | TSHR (0.44) | TSHRTRPA1PBRM1HTR2ATAAR1 | |
| SCHEMBL28474051 | 0.70 | CYP2D6 (0.41) | TSHRTRPA1HTR2ATAAR1CYP1A2 | |
| SCHEMBL27191 | 0.70 | ACHE (0.47) | TSHRHTR2ACYP1A2SMN1; SMN2CYP2D6 | |
| SCHEMBL13233282 | 0.70 | HTR2A (0.39) | TSHRHTR2ATAAR1CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542224-B2 | Synthesis of and compositions containing diaminoacetals and diaminoketals | ADITYA BIRLA CHEMICALS (USA), INC. (US) | 2023-01-03 | — | — | US | disclosed |
| US-20200317604-A1 | SYNTHESIS OF AND COMPOSITIONS CONTAINING DIAMINOACETALS AND DIAMINOKETALS | CONNORA TECHNOLOGIES, INC. | 2020-10-08 | — | — | US | disclosed |
| US-20190284128-A1 | SYNTHESIS OF AND COMPOSITIONS CONTAINING DIAMINOACETALS AND DIAMINOKETALS | ADITYA BIRLA CHEMICALS (USA) LLC | 2019-09-19 | — | — | US | disclosed |
| US-20170114002-A1 | SYNTHESIS OF AND COMPOSITIONS CONTAINING DIAMINOACETALS AND DIAMINOKETALS | CONNORA TECHNOLOGIES, INC. (US) | 2017-04-27 | — | — | US | disclosed |
| US-20150152043-A1 | SYNTHESIS OF AND COMPOSITIONS CONTAINING DIAMINOACETALS AND DIAMINOKETALS | PASTINE STEFAN J (US) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190284128-A1 | SYNTHESIS OF AND COMPOSITIONS CONTAINING DIAMINOACETALS AND DIAMINOKETALS | SRM, AOC1, SAT1 | TSHR 4623/4885TRPA1 1988/4885PBRM1 174/4885 |
| US-20150152043-A1 | SYNTHESIS OF AND COMPOSITIONS CONTAINING DIAMINOACETALS AND DIAMINOKETALS | SRM, AOC1, SAT1 | TSHR 4623/4885TRPA1 1988/4885PBRM1 174/4885 |
| US-20200317604-A1 | SYNTHESIS OF AND COMPOSITIONS CONTAINING DIAMINOACETALS AND DIAMINOKETALS | SRM, AOC1, SAT1 | TSHR 4623/4885TRPA1 1988/4885PBRM1 174/4885 |
| US-11542224-B2 | Synthesis of and compositions containing diaminoacetals and diaminoketals | SRM, AOC1, SAT1 | TSHR 4623/4885TRPA1 1988/4885PBRM1 174/4885 |
| US-20170114002-A1 | SYNTHESIS OF AND COMPOSITIONS CONTAINING DIAMINOACETALS AND DIAMINOKETALS | SRM, AOC1, SAT1 | TSHR 4623/4885TRPA1 1988/4885PBRM1 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.