SCHEMBL16768561

SCHEMBL16768561

Brc1sc(Br)c2c3ccncc3c3cnccc3c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AXL P30530 1/20 0.42
IMPDH2 P12268 1/20 0.37
EP300 Q09472 1/20 0.34
KAT2B Q92831 1/20 0.34
KAT8 Q9H7Z6 1/20 0.34
CHUK O15111 3/20 0.34
KIT P10721 2/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
PRKD3 O94806 1/20 0.33
PRKCG P05129 1/20 0.33
PRKCB P05771 1/20 0.33
PRKCA P17252 1/20 0.33
CSNK2A2 P19784 1/20 0.33
PRKCH P24723 1/20 0.33
PRKCI P41743 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
PRKCE Q02156 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1094972 0.68 AXL (0.36) AXLIMPDH2EP300KAT2BKAT8
SCHEMBL16768527 0.68 TNF (0.43) CHUKCSNK2A2CSNK2BKDM4EALDH1A1
SCHEMBL659162 0.68 IMPDH2 (0.40) AXLIMPDH2CHUKADORA3ADORA2A
SCHEMBL29890100 0.67 AXL (0.72) AXLIMPDH2EP300KAT2BKAT8
SCHEMBL244397 0.67 AXL (0.72) AXLIMPDH2EP300KAT2BKAT8
SCHEMBL22048844 0.67 PARP1 (0.52) CHUKKITKDM4EALDH1A1HTT
SCHEMBL10415807 0.67 KDM4E (0.46) AXLEP300KAT2BKAT8CHUK
SCHEMBL16768526 0.66 NOTUM (0.42) CSNK2A2CSNK2BPRKCZKDM4EALDH1A1
SCHEMBL16768529 0.66 KDM4E (0.38) KDM4EALDH1A1LMNACYP1A2CYP3A4
SCHEMBL743939 0.66 PARP1 (0.55) AXLCHUKKITKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9666809-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-05-30 US disclosed
US-9666809-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-05-30 US disclosed
US-20150155497-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-04 US disclosed
US-20150155497-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-04 US disclosed