SCHEMBL16769520

SCHEMBL16769520

O=C1C=CC(=O)C(c2ccc(C(F)(F)F)cc2C(F)(F)F)=C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 1/20 0.42
CES2 O00748 2/20 0.42
ABCC8 Q09428 1/20 0.38
KCNJ11 Q14654 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
BACE1 P56817 1/20 0.37
TDP2 O95551 1/20 0.36
HSD17B3 P37058 1/20 0.36
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
DAO P14920 1/20 0.35
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
CYP26A1 O43174 2/20 0.34
CYP24A1 Q07973 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16772146 0.79 CES2 (0.37) CES2ABCC8KCNJ11BACE1TDP2
SCHEMBL9839542 0.76 PTPN1 (0.37) PTPN11MAOAMAOBBACE1HSD17B3
SCHEMBL28676412 0.75 TSHR (0.56) CES2ABCC8KCNJ11TDP2EDNRB
SCHEMBL16769518 0.75 BACE1 (0.62) CES2MAOAMAOBBACE1HSD17B3
SCHEMBL12632682 0.73 MAOB (0.55) CES2MAOAMAOBBACE1HSD17B3
SCHEMBL9240847 0.72 TDP2 (0.43) CES2MAOAMAOBBACE1TDP2
SCHEMBL28387735 0.72 MAOA (0.47) PTPN11CES2MAOAMAOBBACE1
SCHEMBL19772650 0.71 PTPN11 (0.37) PTPN11MAOAMAOBHSD17B3GLA
SCHEMBL28387734 0.70 MAOA (0.46) PTPN11MAOAMAOBHSD17B3KDM4E
SCHEMBL30828314 0.69 TDP2 (0.41) CES2MAOAMAOBBACE1TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150155490-A1 ORGANIC COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG DISPLAY CO., LTD. (KR) 2015-06-04 US disclosed
US-20150155490-A1 ORGANIC COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG DISPLAY CO., LTD. (KR) 2015-06-04 US disclosed