Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 4/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749654 | 0.95 | RARB (0.50) | RARBPTPN11MGLLEGFRNPC1 | |
| SCHEMBL19423232 | 0.86 | RARB (0.41) | RARBPTPN11MAPTALDH1A1 | |
| SCHEMBL19423207 | 0.86 | RARB (0.41) | RARBPTPN11MAPTALDH1A1 | |
| SCHEMBL16749640 | 0.82 | RARB (0.68) | RARBPTPN11MAPTALDH1A1 | |
| SCHEMBL19423231 | 0.80 | CYP2D6 (0.42) | RARB | |
| SCHEMBL16769665 | 0.80 | TDP1 (0.47) | TDP1EGFRNPC1RAB9AMAPT | |
| SCHEMBL23353481 | 0.80 | DRD2 (0.38) | RARBPTPN11 | |
| SCHEMBL9164200 | 0.78 | RARB (0.73) | RARBMGLLNPC1RAB9AMAPT | |
| SCHEMBL9820479 | 0.78 | RARB (0.73) | RARBMGLLNPC1RAB9AMAPT | |
| SCHEMBL5352926 | 0.78 | RARB (0.73) | RARBMGLLNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
| US-9102691-B2 | Aluminum metal organic framework materials | TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346759-A1 | Iron Metal Organic Framework Materials | TFRC, FTH1, FECH | TDP1 4073/4885RARB 4562/4885PTPN11 3946/4885 |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | AS3MT, ORAI2, ORAI3 | TDP1 4088/4885RARB 4394/4885PTPN11 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.