Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.58 |
| ▸ | SRC | P12931 | 7/20 | 0.56 |
| ▸ | LCK | P06239 | 3/20 | 0.56 |
| ▸ | TEK | Q02763 | 2/20 | 0.56 |
| ▸ | HCK | P08631 | 1/20 | 0.56 |
| ▸ | ADK | P55263 | 4/20 | 0.52 |
| ▸ | ABL1 | P00519 | 5/20 | 0.50 |
| ▸ | METTL3 | Q86U44 | 5/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29780883 | 1.00 | RET (0.58) | RETSRCLCKTEKHCK | |
| SCHEMBL18640804 | 0.90 | SRC (0.59) | RETSRCLCKADKABL1 | |
| SCHEMBL25612151 | 0.87 | SRC (0.61) | RETSRCLCKTEKADK | |
| SCHEMBL870154 | 0.86 | METTL3 (0.58) | RETSRCLCKTEKADK | |
| SCHEMBL1786788 | 0.83 | RET (0.58) | RETSRCLCKTEKHCK | |
| SCHEMBL29780875 | 0.83 | ADK (0.52) | RETSRCLCKTEKHCK | |
| SCHEMBL16769982 | 0.83 | ADK (0.52) | RETSRCLCKTEKHCK | |
| SCHEMBL18925745 | 0.83 | METTL3 (0.50) | RETADKABL1METTL3KDR | |
| SCHEMBL16769693 | 0.83 | METTL3 (0.50) | RETADKABL1METTL3KDR | |
| SCHEMBL17085734 | 0.82 | ADK (0.51) | RETSRCLCKTEKHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583287-A | Pyridazinone heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-20170158697-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2017-06-08 | — | — | US | disclosed |
| US-20170158697-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2017-06-08 | — | — | US | disclosed |
| WO-2015077866-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2015-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158697-A1 | Protein Kinase Inhibitors | TEC, LCK, SRC | RET 284/4885SRC 3/4885LCK 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.