Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | TACR3 | P29371 | 3/20 | 0.46 |
| ▸ | LCAT | P04180 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321187 | 0.88 | LMNA (0.65) | MEN1KMT2ASMN1; SMN2HRH3LMNA | |
| SCHEMBL16769734 | 0.86 | HRH3 (0.48) | MEN1KMT2ASMN1; SMN2HRH3LMNA | |
| SCHEMBL322942 | 0.82 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2HRH3LMNA | |
| SCHEMBL12639925 | 0.81 | LMNA (0.76) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL16769730 | 0.80 | HRH3 (0.57) | MEN1KMT2ASMN1; SMN2HRH3LCAT | |
| SCHEMBL2005961 | 0.79 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2HRH3LMNA | |
| SCHEMBL30790709 | 0.78 | HRH3 (0.50) | MEN1KMT2ASMN1; SMN2HRH3LMNA | |
| SCHEMBL9219556 | 0.78 | HRH3 (0.50) | MEN1KMT2ASMN1; SMN2HRH3LMNA | |
| SCHEMBL16769739 | 0.77 | CHRNB2 (0.54) | LCATMAPT | |
| Hydrochloric Acid SCHEMBL2004943 | 0.77 | HRH3 (0.49) | MEN1KMT2ASMN1; SMN2HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150575-B2 | Piperidinylpyrazolopyridine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-10-06 | — | — | US | disclosed |
| US-20150152102-A1 | PIPERIDINYLPYRAZOLOPYRIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152102-A1 | PIPERIDINYLPYRAZOLOPYRIDINE DERIVATIVE | LCAT, LPL, LCLAT1 | MEN1 4861/4885KMT2A 1626/4885SMN1; SMN2 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.