Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015102 | 0.95 | NPC1 (0.51) | SMN1; SMN2RAB9AADORA1ADORA3NPC1 | |
| SCHEMBL3626598 | 0.94 | DEGS1 (0.53) | SMN1; SMN2RAB9ANPC1GLAMAPK1 | |
| SCHEMBL11016976 | 0.94 | DEGS1 (0.53) | SMN1; SMN2RAB9ANPC1GLAMAPK1 | |
| SCHEMBL11018471 | 0.94 | DEGS1 (0.53) | SMN1; SMN2RAB9ANPC1GLAMAPK1 | |
| SCHEMBL10931578 | 0.91 | ADORA3 (0.46) | ADORA1ADORA3HTR1FALDH1A1KDM4E | |
| SCHEMBL1334904 | 0.84 | ADORA3 (0.43) | SMN1; SMN2RAB9AADORA1ADORA3NPC1 | |
| Ribose (Furanose) SCHEMBL11402368 | 0.84 | HTR1F (0.39) | SMN1; SMN2RAB9AADORA1ADORA3NPC1 | |
| SCHEMBL1966349 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9AADORA1ADORA3NPC1 | |
| Ribose (Furanose) SCHEMBL11364922 | 0.80 | HTR1F (0.39) | SMN1; SMN2RAB9ANPC1GLAMAPK1 | |
| Ribose (Furanose) SCHEMBL11407725 | 0.80 | DEGS1 (0.41) | SMN1; SMN2RAB9ANPC1GLAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024250923-A1 | CHEMICALLY MODIFIED NUCLEOSIDE, CHEMICALLY MODIFIED NUCLEOSIDE TRIPHOSPHATE AND USE THEREOF | 中国科学院深圳先进技术研究院 | 2024-12-12 | — | — | WO | disclosed |
| WO-2024250607-A1 | CHEMICALLY MODIFIED CYTIDINE TRIPHOSPHATE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院深圳先进技术研究院 | 2024-12-12 | — | — | WO | disclosed |
| CN-119080855-A | Chemically modified cytosine nucleoside triphosphate and preparation method and application thereof | 中国科学院深圳先进技术研究院 | 2024-12-06 | — | — | CN | disclosed |
| US-20160312261-A1 | ENZYMATIC PRODUCTION OF CYTOSINIC NUCLEOSIDE ANALOGUES | PLASMIA BIOTECH, S.L. (ES) | 2016-10-27 | — | — | US | disclosed |
| US-20160312261-A1 | ENZYMATIC PRODUCTION OF CYTOSINIC NUCLEOSIDE ANALOGUES | PLASMIA BIOTECH, S.L. (ES) | 2016-10-27 | — | — | US | disclosed |
| US-20160312261-A1 | ENZYMATIC PRODUCTION OF CYTOSINIC NUCLEOSIDE ANALOGUES | PLASMIA BIOTECH, S.L. (ES) | 2016-10-27 | — | — | US | disclosed |
| EP-2883959-A1 | Enzymatic production of cytosinic nucleoside analogues | Plasmia Biotech, S.L. (ES) | 2015-06-17 | — | — | EP | disclosed |
| EP-2883959-A1 | Enzymatic production of cytosinic nucleoside analogues | Plasmia Biotech, S.L. (ES) | 2015-06-17 | — | — | EP | disclosed |