Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTR1F | P30939 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774439 | 0.91 | SMN1; SMN2 (0.51) | ADORA3ADORA1HTR1FKDM4EALDH1A1 | |
| SCHEMBL11015102 | 0.89 | NPC1 (0.51) | ADORA3ADORA1HTR1FALDH1A1HPGD | |
| SCHEMBL11018471 | 0.88 | DEGS1 (0.53) | HTR1FALDH1A1 | |
| SCHEMBL3626598 | 0.88 | DEGS1 (0.53) | HTR1FALDH1A1 | |
| SCHEMBL11016976 | 0.88 | DEGS1 (0.53) | HTR1FALDH1A1 | |
| SCHEMBL1334904 | 0.87 | ADORA3 (0.43) | ADORA3ADORA1ADORA2AHTR1FKDM4E | |
| SCHEMBL1966349 | 0.86 | SMN1; SMN2 (0.37) | ADORA3ADORA1ADORA2AHTR1FALDH1A1 | |
| Ribose (Furanose) SCHEMBL11407593 | 0.83 | PYGB (0.43) | ADORA3ADORA1ADORA2AHTR1FCCNA2 | |
| SCHEMBL21219850 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGD | |
| SCHEMBL13892050 | 0.79 | PARP1 (0.51) | ADORA1ADORA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447923-B | Methyl nucleoside derivatives of 2 ' deoxidation, 2 ' fluorine 2 ' and preparation method thereof and the purposes in pharmacy | 中国药科大学 | 2018-03-30 | — | — | CN | claimed |
| JP-60252493-A | — | — | None | — | — | JP | disclosed |
| WO-2024250607-A1 | CHEMICALLY MODIFIED CYTIDINE TRIPHOSPHATE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院深圳先进技术研究院 | 2024-12-12 | — | — | WO | disclosed |
| WO-2024250923-A1 | CHEMICALLY MODIFIED NUCLEOSIDE, CHEMICALLY MODIFIED NUCLEOSIDE TRIPHOSPHATE AND USE THEREOF | 中国科学院深圳先进技术研究院 | 2024-12-12 | — | — | WO | disclosed |
| CN-119080855-A | Chemically modified cytosine nucleoside triphosphate and preparation method and application thereof | 中国科学院深圳先进技术研究院 | 2024-12-06 | — | — | CN | disclosed |
| CN-104447923-B | Methyl nucleoside derivatives of 2 ' deoxidation, 2 ' fluorine 2 ' and preparation method thereof and the purposes in pharmacy | 中国药科大学 | 2018-03-30 | — | — | CN | disclosed |
| JP-S60252493-A | PREPARATION OF CYTIDINE DERIVATIVE | TAKEDA CHEM IND LTD | 1985-12-13 | — | — | JP | disclosed |
| EP-0136693-A2 | Production of cytidine derivatives | Takeda Chemical Industries, Ltd. (JP) | 1985-04-10 | — | — | EP | disclosed |