Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.43 |
| ▸ | HTR1F | P30939 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10931578 | 0.87 | ADORA3 (0.46) | ADORA3ADORA1ADORA2AADORA2BHTR1F | |
| SCHEMBL16774439 | 0.84 | SMN1; SMN2 (0.51) | ADORA3ADORA1HTR1FNPC1RAB9A | |
| SCHEMBL11015102 | 0.83 | NPC1 (0.51) | ADORA3ADORA1HTR1FHTR1DHTR1B | |
| SCHEMBL21219850 | 0.83 | ALDH1A1 (0.45) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| Ribose (Furanose) SCHEMBL11397241 | 0.82 | OGA (0.44) | HTR1FHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL13892050 | 0.82 | PARP1 (0.51) | ADORA1ADORA2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1966349 | 0.82 | SMN1; SMN2 (0.37) | ADORA3ADORA1ADORA2AHTR1FNPC1 | |
| SCHEMBL11018471 | 0.82 | DEGS1 (0.53) | HTR1FHTR1DHTR1BNPC1POLB | |
| SCHEMBL11016976 | 0.82 | DEGS1 (0.53) | HTR1FHTR1DHTR1BNPC1POLB | |
| SCHEMBL3626598 | 0.82 | DEGS1 (0.53) | HTR1FHTR1DHTR1BNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024123-A1 | NOVEL CITICOLINE DERIVATIVES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-30 | — | — | WO | claimed |
| CN-108409818-B | Method for synthesizing cytosine nucleoside | 新乡拓新药业股份有限公司 | 2020-09-11 | — | — | CN | claimed |
| WO-2025024123-A1 | NOVEL CITICOLINE DERIVATIVES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-30 | — | — | WO | disclosed |
| WO-2024250607-A1 | CHEMICALLY MODIFIED CYTIDINE TRIPHOSPHATE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院深圳先进技术研究院 | 2024-12-12 | — | — | WO | disclosed |
| WO-2024250923-A1 | CHEMICALLY MODIFIED NUCLEOSIDE, CHEMICALLY MODIFIED NUCLEOSIDE TRIPHOSPHATE AND USE THEREOF | 中国科学院深圳先进技术研究院 | 2024-12-12 | — | — | WO | disclosed |
| CN-119080855-A | Chemically modified cytosine nucleoside triphosphate and preparation method and application thereof | 中国科学院深圳先进技术研究院 | 2024-12-06 | — | — | CN | disclosed |
| EP-3184112-B1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSYL)CYTOSINE | FUJIFILM CORP (JP) | 2020-12-23 | — | — | EP | disclosed |
| CN-108409818-B | Method for synthesizing cytosine nucleoside | 新乡拓新药业股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-10570112-B2 | Synthetic intermediate of 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)cytosine, synthetic intermediate of thionucleoside, and method for producing the same | FUJIFILM CORPORATION (JP) | 2020-02-25 | — | — | US | disclosed |
| US-20180327377-A1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSYL)CYTOSINE, SYNTHETIC INTERMEDIATE OF THIONUCLEOSIDE, AND METHOD FOR PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2018-11-15 | — | — | US | disclosed |
| CN-104447923-B | Methyl nucleoside derivatives of 2 ' deoxidation, 2 ' fluorine 2 ' and preparation method thereof and the purposes in pharmacy | 中国药科大学 | 2018-03-30 | — | — | CN | disclosed |
| US-7371818-B2 | Polypeptide and DNA thereof | SHIONOGI & CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| EP-1354890-B1 | CHORDIN-LIKE POLYPEPTIDES AND DNA THEREOF | SHIONOGI & CO (JP) | 2007-08-08 | — | — | EP | disclosed |
| WO-2007030890-A1 | A MARKER FOR PROLONGED RUPTURE OF MEMBRANES | BIO SOURCE (WUHAN) TECHNOLOGY LTD (CN) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007030889-A1 | METHOD OF DIAGNOSING PRE-ECLAMPSIA | VOROTELIAK VICTOR (AU) | 2007-03-22 | — | — | WO | disclosed |
| US-20050158719-A1 | Using tumor maker protein as diagnostic/prognostic tool in detection of neovascularization, vascular, inflammatory, reproductive system, central nervous and cell proliferative disorders | SHIONOGI & CO., LTD. (JP) | 2005-07-21 | — | — | US | disclosed |
| US-20040110921-A1 | Novel polypeptide and dna thereof | SHIONOGI & CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
| EP-1391512-A1 | POLYPEPTIDE SERVING AS ANGIOGENIC MARKER AND DNA THEREOF | SHIONOGI & CO., LTD. (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-1354890-A1 | NOVEL POLYPEPTIDE AND DNA THEREOF | SHIONOGI & CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
| EP-0136693-A2 | Production of cytidine derivatives | Takeda Chemical Industries, Ltd. (JP) | 1985-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570112-B2 | Synthetic intermediate of 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)cytosine, synthetic intermediate of thionucleoside, and method for producing the same | TYMS, TYMP, RRM2B | ADORA3 436/4885ADORA1 282/4885ADORA2A 464/4885 |
| US-20180327377-A1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSYL)CYTOSINE, SYNTHETIC INTERMEDIATE OF THIONUCLEOSIDE, AND METHOD FOR PRODUCING THE SAME | TYMS, TYMP, RRM2B | ADORA3 427/4885ADORA1 281/4885ADORA2A 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.