Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.38 |
| ▸ | LGALS4 | P56470 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774476 | 0.78 | ADRB2 (0.45) | POLBKMT2APTPN2PTPN1MEN1 | |
| SCHEMBL15481817 | 0.72 | ALDH1A1 (0.51) | POLBKMT2APTPN2PTPN1MEN1 | |
| SCHEMBL17471056 | 0.72 | ALDH1A1 (0.51) | POLBKMT2APTPN2PTPN1MEN1 | |
| SCHEMBL28425890 | 0.71 | LGALS3 (0.46) | POLBKMT2APTPN2PTPN1MEN1 | |
| SCHEMBL18298134 | 0.71 | PTPN1 (0.42) | POLBKMT2APTPN1MEN1MAPT | |
| SCHEMBL16685961 | 0.69 | HTT (0.47) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL14686864 | 0.69 | HTT (0.54) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL306161 | 0.67 | POLB (0.81) | POLBKMT2APTPN2PTPN1MEN1 | |
| SCHEMBL1163261 | 0.67 | ADRB2 (0.56) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20776672 | 0.66 | PTPN2 (0.50) | POLBKMT2APTPN2PTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184112-B1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSYL)CYTOSINE | FUJIFILM CORP (JP) | 2020-12-23 | — | — | EP | disclosed |
| EP-3184112-A1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-SS-D-ARABINOFURANOSYL)CYTOSINE | Fujifilm Corporation (JP) | 2017-06-28 | — | — | EP | disclosed |
| EP-2883866-A1 | INTERMEDIATE FOR SYNTHESIS OF 1-(2-DEOXY-2-FLUORO-4-THIO-beta-D-ARABINOFURANOSYL) CYTOSINE, INTERMEDIATE FOR SYNTHESIS OF THIONUCLEOSIDE, AND METHODS FOR PRODUCING THESE INTERMEDIATES | FUJIFILM Corporation (JP) | 2015-06-17 | — | — | EP | disclosed |