Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 2/20 | 0.37 |
| ▸ | PGK2 | P07205 | 2/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572567 | 0.87 | HDAC4 (0.39) | DAOCYSLTR2CYSLTR1PTGIRLMNA | |
| SCHEMBL11198497 | 0.81 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1 | |
| SCHEMBL1705960 | 0.77 | TAAR1 (0.53) | DAO | |
| SCHEMBL13679163 | 0.77 | DAO (0.48) | DAOCYSLTR2CYSLTR1PGK1PGK2 | |
| SCHEMBL21323482 | 0.77 | DAO (0.48) | DAO | |
| SCHEMBL10317438 | 0.77 | DAO (0.48) | DAO | |
| Formic Acid SCHEMBL28261576 | 0.77 | LPL (0.49) | DAOCYSLTR2CYSLTR1 | |
| SCHEMBL4227993 | 0.76 | TYR (0.41) | DAOCYSLTR2CYSLTR1 | |
| SCHEMBL31634534 | 0.76 | TYR (0.41) | DAOCYSLTR2CYSLTR1 | |
| SCHEMBL30428130 | 0.75 | SMN1; SMN2 (0.58) | DAOCYSLTR2CYSLTR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150152040-A1 | Method For The Preparation Of Cinacalcet And Intermediates And Impurities Thereof | AMNEAL PHARMACEUTICALS LLC (US) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152040-A1 | Method For The Preparation Of Cinacalcet And Intermediates And Impurities Thereof | CMA1, SI, ALDH1A1 | DAO 2271/4885CYSLTR2 2113/4885CYSLTR1 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.