Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16776030 | 0.89 | PRMT5 (0.37) | MCHR1TRPV1HRH4HRH3NAPEPLD | |
| SCHEMBL16776036 | 0.87 | HRH4 (0.37) | MCHR1HRH4HRH3NAPEPLDPDE10A | |
| SCHEMBL19706148 | 0.85 | NPC1 (0.39) | MCHR1ACACBTRPV1HRH4HRH3 | |
| SCHEMBL17618339 | 0.83 | HTR2C (0.41) | MCHR1TRPV1HRH4HRH3HTR2C | |
| SCHEMBL16238365 | 0.81 | HTR2C (0.41) | MCHR1TRPV1HRH4HRH3HTR2C | |
| SCHEMBL16754613 | 0.81 | HTR2C (0.41) | MCHR1TRPV1HRH4HRH3HTR2C | |
| Hydrochloric Acid SCHEMBL16238890 | 0.80 | HTR2C (0.40) | MCHR1TRPV1HRH4HRH3HTR2C | |
| Hydrochloric Acid SCHEMBL16238891 | 0.80 | HTR2C (0.40) | MCHR1TRPV1HRH4HRH3HTR2C | |
| SCHEMBL19670269 | 0.80 | MCHR1 (0.38) | MCHR1ACACBTRPV1HRH4HRH3 | |
| SCHEMBL16776218 | 0.75 | RPS6KA3 (0.42) | RPS6KA3RPS6KA2HRH3HTR2CCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150152108-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC | 2015-06-04 | — | — | US | disclosed |
| US-20150152108-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152108-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | SIRT1, SIRT3, SIRT2 | RPS6KA3 2368/4885RPS6KA2 2318/4885MCHR1 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.