Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1677879 | 1.00 | MAPT (0.67) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL7370645 | 0.94 | MAPT (0.60) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL6998661 | 0.91 | MAPT (0.67) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL6998663 | 0.91 | MAPT (0.67) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL11018799 | 0.89 | MAPT (0.55) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL10937052 | 0.89 | MAPT (0.55) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL10937055 | 0.89 | MAPT (0.55) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL11018812 | 0.89 | MAPT (0.55) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL29130643 | 0.87 | MAOB (0.72) | MAPTALDH1A1HPGDNPSR1HTT | |
| SCHEMBL11621360 | 0.81 | MAPT (0.56) | MAPTALDH1A1KMT2AHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747059-A1 | PERVAPORATION COMPOSITE MEMBRANES | McMaster University (CA) | 2007-01-31 | — | — | EP | claimed |
| US-20060000778-A1 | high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers | MCMASTER UNIVERSITY (CA) | 2006-01-05 | — | — | US | claimed |
| WO-2005102503-A1 | PERVAPORATION COMPOSITE MEMBRANES | MCMASTER UNIVERSITY (CA) | 2005-11-03 | — | — | WO | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| WO-2005075471-A2 | THIAZOL-COMPOUNDS AS 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | BIOVITRUM AB (SE) | 2005-08-18 | — | — | WO | claimed |
| CN-118684651-A | Compound capable of regulating and controlling fibroblast growth factor receptor 2 protein level and preparation method and application thereof | 四川大学 | 2024-09-24 | — | — | CN | disclosed |
| EP-2226192-B1 | DRYING SUBSTANCES, PREPARATION AND USE THEREOF | ORIDION MEDICAL 1987 LTD (IL) | 2016-08-31 | — | — | EP | disclosed |
| EP-2226116-B1 | Drying tube, preparation and use thereof | ORIDION MEDICAL 1987 LTD (IL) | 2016-04-20 | — | — | EP | disclosed |
| US-20150283519-A1 | DRYING SUBSTANCES, PREPARATION AND USE THEREOF | ORIDION MEDICAL 1987 LTD. (IL) | 2015-10-08 | — | — | US | disclosed |
| US-9090766-B2 | Drying substances, preparation and use thereof | ORIDION MEDICAL 1987 LTD. (IL) | 2015-07-28 | — | — | US | disclosed |
| US-9067035-B2 | Drying substances, preparation and use thereof | ORIDION MEDICAL (1987) LTD. (IL) | 2015-06-30 | — | — | US | disclosed |
| US-20140230652-A1 | DRYING SUBSTANCES, PREPARATION AND USE THEREOF | ORIDION MEDICAL (1987) LTD. (IL) | 2014-08-21 | — | — | US | disclosed |
| US-4377586-A | Diuretic 2,6-diaryl-4-pyridine carboxylic acids | THE UPJOHN COMPANY (US) | 1983-03-22 | — | — | US | disclosed |
| US-4374249-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-02-15 | — | — | US | disclosed |
| EP-0064385-A1 | 2,6-Diaryl-pyridinecarboxylic acids and their therapeutic utility | THE UPJOHN COMPANY (US) | 1982-11-10 | — | — | EP | disclosed |
| US-4221804-A | Mercaptoacyldihydropyrazole carboxylic acid derivatives | ROVNYAK GEORGE C | 1980-09-09 | — | — | US | disclosed |
| US-4211786-A | Mercaptoacyldihydropyrazole carboxylic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1980-07-08 | — | — | US | disclosed |
| US-4127656-A | Method of inhibiting lipogensis with 3-(benzoyl)oxiranecarboxamides | SHELL OIL COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4091221-A | LIPOGENESIS INHIBITORS | SHELL OIL COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-3931159-A | BACTERICIDE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | MAPT 3607/4885ALDH1A1 67/4885KMT2A 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.