Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.65 |
| ▸ | CES1 | P23141 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998663 | 0.91 | MAPT (0.67) | MAOBCYP1B1MAPTLMNAALDH1A1 | |
| SCHEMBL6998661 | 0.91 | MAPT (0.67) | MAOBCYP1B1MAPTLMNAALDH1A1 | |
| SCHEMBL1677879 | 0.87 | MAPT (0.67) | MAOBCYP1B1MAPTLMNAALDH1A1 | |
| SCHEMBL1677880 | 0.87 | MAPT (0.67) | MAOBCYP1B1MAPTLMNAALDH1A1 | |
| SCHEMBL2954324 | 0.86 | MAPT (0.70) | MAOBCYP1B1MAPTLMNAALDH1A1 | |
| SCHEMBL11073619 | 0.86 | MAPT (0.70) | MAOBCYP1B1MAPTLMNAALDH1A1 | |
| SCHEMBL2954318 | 0.86 | MAPT (0.70) | MAOBCYP1B1MAPTLMNAALDH1A1 | |
| SCHEMBL196424 | 0.84 | CYP1B1 (1.00) | MAOBCYP1B1MAPTLMNAALDH1A1 | |
| SCHEMBL10415521 | 0.84 | CYP1B1 (1.00) | MAOBCYP1B1MAPTLMNAALDH1A1 | |
| 4-Chloro Chalcone SCHEMBL197311 | 0.84 | MAOB (1.00) | MAOBCYP1B1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285415-A | Cis-2-alkene-1, 4-diketone derivative and synthetic method thereof | 浙江师范大学 | 2023-12-26 | — | — | CN | disclosed |