SCHEMBL467546

SCHEMBL467546

O=C(O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59
HDAC5 Q9UQL6 1/20 0.59
POLB P06746 2/20 0.49
CYP2C9 P11712 5/20 0.48
CYP2C19 P33261 4/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
CYP2D6 P10635 2/20 0.48
BRD4 O60885 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TSHR P16473 2/20 0.48
ALOX15 P16050 1/20 0.48
CNR1 P21554 2/20 0.47
GABBR2 O75899 3/20 0.47
GABBR1 Q9UBS5 3/20 0.47
LMNA P02545 2/20 0.47
CYP3A4 P08684 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
NFKB1 P19838 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL933980 0.98 HDAC4 (0.57) HDAC4HDAC7HDAC5POLBCYP2C9
SCHEMBL9337191 0.93 CNR1 (0.56) HDAC4HDAC7HDAC5KMT2AMEN1
SCHEMBL13114156 0.89 HDAC4 (0.50) HDAC4HDAC7HDAC5POLBCYP2C9
SCHEMBL7973591 0.84 HPGD (0.58) POLBKMT2AMEN1TSHRLMNA
SCHEMBL11287246 0.82 HDAC4 (0.61) HDAC4HDAC7HDAC5CYP2C9CYP2C19
SCHEMBL5220963 0.80 SRC (0.61) HDAC4HDAC7HDAC5POLBCYP2C9
SCHEMBL933979 0.80 HDAC4 (0.59) HDAC4HDAC7HDAC5CYP2C9CYP2C19
SCHEMBL19007014 0.80 CYP2C9 (0.52) POLBCYP2C9KMT2AMEN1CYP2D6
SCHEMBL16781990 0.79 CNR1 (0.56) HDAC4HDAC7HDAC5KMT2AMEN1
SCHEMBL9797335 0.78 CYP2C9 (0.47) HDAC4HDAC7HDAC5POLBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-113637642-A Hybridoma cell strain capable of secreting monoclonal antibody of dicofol and application of hybridoma cell strain 江南大学 2021-11-12 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
EP-1649029-B1 A METHOD OF PRODUCING A LOW MOLECULAR WEIGHT PLANT SECONDARY METABOLITE IN A YEAST CELL EVOLVA SA (CH) 2014-12-17 EP claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
CN-122059950-A Compounds with proteasome agonistic activity, preparation method and application thereof 浙大城市学院 2026-05-19 CN disclosed
US-4115578-A FUNGICIDES ROHM AND HAAS COMPANY (US) 1978-09-19 US disclosed
US-4105762-A Metal salt complexes of 1-substituted aralkyl imidazoles, and methods and compositions for controlling phytopathogenic fungi using them ROHM AND HAAS COMPANY (US) 1978-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS HDAC4 2837/4885HDAC7 3036/4885HDAC5 2180/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS HDAC4 2837/4885HDAC7 3036/4885HDAC5 2180/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 HDAC4 1701/4885HDAC7 2054/4885HDAC5 2620/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 HDAC4 802/4885HDAC7 1729/4885HDAC5 966/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS HDAC4 2837/4885HDAC7 3036/4885HDAC5 2180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.