Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16784578 | 0.94 | SMN1; SMN2 (0.43) | HPGDHTTSMN1; SMN2DRD2TSHR | |
| SCHEMBL13575095 | 0.91 | HPGD (0.41) | HPGDHTTSMN1; SMN2DRD2TSHR | |
| SCHEMBL12628925 | 0.85 | SMN1; SMN2 (0.43) | HPGDHTTSMN1; SMN2DRD2TSHR | |
| SCHEMBL16221669 | 0.85 | HPGD (0.39) | HPGDHTTSMN1; SMN2DRD2TSHR | |
| SCHEMBL20752871 | 0.85 | SMN1; SMN2 (0.44) | HPGDHTTSMN1; SMN2DRD2TSHR | |
| SCHEMBL20752666 | 0.85 | SMN1; SMN2 (0.44) | HPGDHTTSMN1; SMN2DRD2TSHR | |
| SCHEMBL16784579 | 0.85 | DRD2 (0.42) | HPGDHTTSMN1; SMN2DRD2TSHR | |
| SCHEMBL14978042 | 0.84 | FOLH1 (0.43) | HPGDHTTSMN1; SMN2DRD2TSHR | |
| SCHEMBL14819092 | 0.84 | SMN1; SMN2 (0.43) | HPGDHTTSMN1; SMN2DRD2TSHR | |
| SCHEMBL16404363 | 0.84 | DRD2 (0.38) | HPGDHTTSMN1; SMN2DRD2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150297681-A1 | Pegylated Insulin Lispro Compounds | ELI LILLY AND COMPANY (US) | 2015-10-22 | — | — | US | disclosed |
| US-9050371-B2 | PEGylated insulin lispro compounds | ELI LILLY AND COMPANY (US) | 2015-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297681-A1 | Pegylated Insulin Lispro Compounds | IAPP, IDE, LIPE | HPGD 1041/4885HTT 354/4885SMN1; SMN2 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.