Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CDK11B | P21127 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16788868 | 0.88 | PDGFRB (0.47) | NUDT1PDGFRBKITPDGFRACDK11B | |
| SCHEMBL14949336 | 0.88 | PDGFRB (0.41) | RAB9ANPC1PDGFRBKITPDGFRA | |
| SCHEMBL14949247 | 0.88 | RAB9A (0.37) | NUDT1RAB9ANPC1SMN1; SMN2NOD1 | |
| SCHEMBL14949288 | 0.86 | RAB9A (0.39) | NUDT1RAB9ANPC1SMN1; SMN2NOD1 | |
| SCHEMBL14949279 | 0.85 | PDGFRB (0.37) | NUDT1RAB9ANPC1SMN1; SMN2NOD1 | |
| SCHEMBL14949260 | 0.82 | KIT (0.37) | RAB9ANPC1SMN1; SMN2NOD1PDGFRB | |
| SCHEMBL14949256 | 0.81 | ROCK1 (0.39) | RAB9ANPC1NOD1PDGFRBKIT | |
| SCHEMBL14949266 | 0.81 | PDGFRB (0.40) | RAB9ANPC1NOD1PDGFRBKIT | |
| SCHEMBL14949274 | 0.80 | PDGFRB (0.41) | RAB9ANPC1SMN1; SMN2NOD1PDGFRB | |
| SCHEMBL14949261 | 0.80 | NPC1 (0.34) | RAB9ANPC1SMN1; SMN2NOD1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212151-B2 | Heterocyclic compounds useful for kinase inhibition | AMITECH THERAPEUTIC SOLUTIONS, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150158828-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | AMITECH THERAPEUTIC SOLUTIONS, INC. | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158828-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | MAP4K2, MAP3K20, MAP3K19 | NUDT1 1966/4885RAB9A 1281/4885NPC1 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.