⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Mononitrosopiperazine SCHEMBL28228759 | 0.97 | — | — | |
| SCHEMBL7972119 | 0.89 | — | — | |
| SCHEMBL18650479 | 0.82 | CXCR4 (0.35) | — | |
| N-Mononitrosopiperazine SCHEMBL28217485 | 0.77 | ADRB1 (0.44) | — | |
| SCHEMBL3262072 | 0.75 | — | — | |
| N,N'-Dinitrosopiperazine SCHEMBL2353649 | 0.75 | — | — | |
| Pyrrolidine SCHEMBL11276346 | 0.75 | CA2 (0.35) | — | |
| Pivalate SCHEMBL19638332 | 0.74 | SIGMAR1 (0.33) | — | |
| SCHEMBL606668 | 0.69 | — | — | |
| SCHEMBL11507080 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361181-A1 | DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER | HSUSTAINABILITY GMBH (DE) | 2025-11-27 | — | — | US | claimed |
| EP-4565543-A1 | DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER | Heidelberg Materials AG (DE) | 2025-06-11 | — | — | EP | claimed |
| CN-118978495-A | Preparation method of 1-amino-4-cyclopentyl piperazine | 辽宁友之泰医药科技有限公司 | 2024-11-19 | — | — | CN | claimed |
| WO-2024028219-A1 | DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER | HEIDELBERG MATERIALS AG (DE) | 2024-02-08 | — | — | WO | claimed |
| EP-4317103-A1 | DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER | Heidelberg Materials AG (DE) | 2024-02-07 | — | — | EP | claimed |
| WO-2013106831-A1 | THERMAL DESTRUCTION OF NITROSAMINE IN CO2 CAPTURE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-07-18 | — | — | WO | claimed |
| US-3997539-A | HYPOTENSIVE, TRANQUILIZER | AMERICAN HOECHST CORPORATION (US) | 1976-12-14 | — | — | US | claimed |
| JP-8283159-A | — | — | None | — | — | JP | disclosed |
| US-20260098021-A1 | Nitrosation Reagents and Methods | UNIV CALIFORNIA (US) | 2026-04-09 | — | — | US | disclosed |
| CN-114306247-B | Pharmaceutical composition containing rifapentine and preparation method thereof | 江苏先声药业有限公司 | 2026-03-06 | — | — | CN | disclosed |
| US-20250361181-A1 | DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER | HSUSTAINABILITY GMBH (DE) | 2025-11-27 | — | — | US | disclosed |
| US-12459909-B2 | Nitrosation reagents and methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-11-04 | — | — | US | disclosed |
| EP-4565543-A1 | DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER | Heidelberg Materials AG (DE) | 2025-06-11 | — | — | EP | disclosed |
| US-4797399-A | ANTIINFLAMMATORY AGENTS, ANTICOAGULANTS ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0232740-A1 | N-containing fused heterocyclic compounds, processes for the preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-19 | — | — | EP | disclosed |
| US-4267175-A | FOR USE AS AN ANTIEMETIC, AND TREATMENT FOR GASTROINTESTINAL DISORDERS | BEECHAM GROUP LIMITED (GB) | 1981-05-12 | — | — | US | disclosed |
| US-4024258-A | Composition of and method for reducing hypertension with a 1-[1-(indol-3-ylethyl)-piperazin-4-yl]-3-substituted urea | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3997539-A | HYPOTENSIVE, TRANQUILIZER | AMERICAN HOECHST CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3948918-A | HYPOTENSIVE | AMERICAN HOECHST CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |
| US-3937701-A | 1-(10-Cyano/halo-5H-dibenzo[a,d]cyclohepten-5-yl)-4-[(pyridylmethylene)amino]piperazines | G. D. SEARLE & CO. (US) | 1976-02-10 | — | — | US | disclosed |