Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.31 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679399 | 0.85 | NR1H2 (0.37) | NR1H2NR1H3FFAR1KIF11 | |
| SCHEMBL4936165 | 0.85 | NR1H2 (0.42) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1678906 | 0.81 | ADAMTS4 (0.41) | NR1H2NR1H3ADAMTS4MMP13FFAR1 | |
| SCHEMBL1678810 | 0.80 | NR1H2 (0.35) | NR1H2NR1H3ADAMTS4MMP13PPARG | |
| SCHEMBL4935667 | 0.79 | NR1H2 (0.53) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4935619 | 0.77 | RXRA (0.46) | NR1H2NR1H3PPARDFFAR1KIF11 | |
| SCHEMBL1679125 | 0.74 | NR1H2 (0.38) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1679696 | 0.72 | NR1H2 (0.40) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1679382 | 0.71 | CYP2C19 (0.44) | FFAR1KIF11 | |
| SCHEMBL1678615 | 0.69 | NR1H2 (0.44) | NR1H2NR1H3FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |