Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16762732 | 0.90 | ESR2 (0.56) | DGAT1JAK2JAK1TYK2JAK3 | |
| SCHEMBL10188553 | 0.90 | ESR2 (0.56) | DGAT1JAK2JAK1TYK2JAK3 | |
| SCHEMBL17327388 | 0.90 | ESR2 (0.56) | DGAT1JAK2JAK1TYK2JAK3 | |
| SCHEMBL3302331 | 0.88 | DGAT1 (0.48) | DGAT1JAK2JAK1TYK2JAK3 | |
| SCHEMBL14113473 | 0.88 | DGAT1 (0.48) | DGAT1JAK2JAK1TYK2JAK3 | |
| SCHEMBL3302329 | 0.88 | DGAT1 (0.48) | DGAT1JAK2JAK1TYK2JAK3 | |
| SCHEMBL180554 | 0.88 | IDO1 (0.49) | DGAT1JAK2JAK1TYK2JAK3 | |
| SCHEMBL602376 | 0.87 | CYP2C9 (0.48) | DGAT1JAK2JAK1TYK2JAK3 | |
| SCHEMBL180806 | 0.87 | CYP2C9 (0.48) | DGAT1JAK2JAK1TYK2JAK3 | |
| SCHEMBL17729966 | 0.87 | ALDH1A1 (0.48) | DGAT1JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11932601-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2022-09-01 | — | — | US | disclosed |
| US-11242319-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-20190092729-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. | 2019-03-28 | — | — | US | disclosed |
| EP-3215141-A2 | IMMUNOREGULATORY AGENTS | Flexus Biosciences, Inc. (US) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016073738-A2 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. (US) | 2016-05-12 | — | — | WO | disclosed |
| US-9271969-B2 | Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme | KAINOS MEDICINE, INC. (KR) | 2016-03-01 | — | — | US | disclosed |
| US-20150157611-A1 | COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL O-ACYLTRANSFERASE TYPE I ENZYME | KAINOS MEDICINE, INC. (KR) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242319-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | DGAT1 854/4885JAK2 1134/4885JAK1 1436/4885 |
| US-20150157611-A1 | COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL O-ACYLTRANSFERASE TYPE I ENZYME | DGAT1, DGAT2, SOAT1 | DGAT1 1/4885JAK2 4042/4885JAK1 3748/4885 |
| US-20190092729-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | DGAT1 854/4885JAK2 1134/4885JAK1 1436/4885 |
| US-11932601-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | DGAT1 854/4885JAK2 1134/4885JAK1 1436/4885 |
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | DGAT1 854/4885JAK2 1134/4885JAK1 1436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.